Comprehensive PRISMA Based Systematic Review: Exploring the Phytochemistry, Pharmacological Profile and Clinical aspects of Panax ginseng.

IF 2.9 4区医学 Q3 CHEMISTRY, MEDICINAL

Current topics in medicinal chemistry Pub Date : 2024-10-18 DOI:10.2174/0115680266344493241014082257

Sonia Singh, Ronak Agrawal, Himanshu Sharma

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引用次数: 0

Abstract

Introduction: Ginseng, a perennial herb belonging to the Araliaceae family, is renowned for its traditional and folk uses. The Panax ginseng C.A. Meyer species is predominantly found in Asian countries, including Japan, China, and Korea.

Materials and methods: This manuscript offers valuable insights into the cultivation, collection, morphology, phytochemistry, pharmacological properties, and clinical studies of Ginseng. The data was meticulously gathered from diverse electronic resources, such as PubMed, Scopus, Science Direct, and Web of Science, spanning from 1963 to 2023.

Results: Ginseng contains various bioactive components, including carbohydrates, polyacetylenic alcohols, polysaccharides, ginsenosides, peptides, vitamins, and fatty acids. The biological attributes of ginsenosides, which include anti-diabetic, anti-cancer, anti-oxidant, and anti-inflammatory activities, render them especially remarkable.

Conclusion: This manuscript comprehensively explores the versatile therapeutic applications of ginseng in the treatment of various types of cancers.

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基于 PRISMA 的全面系统综述：探索人参的植物化学、药理特征和临床方面。

简介人参是一种多年生草本植物，属于旱金莲科，以其传统和民间用途而闻名。人参主要分布在亚洲国家，包括日本、中国和韩国：本手稿对人参的栽培、采集、形态、植物化学、药理特性和临床研究提供了宝贵的见解。这些数据是从 PubMed、Scopus、Science Direct 和 Web of Science 等各种电子资源中精心收集的，时间跨度从 1963 年到 2023 年：人参含有多种生物活性成分，包括碳水化合物、多乙酰醇、多糖、人参皂苷、肽、维生素和脂肪酸。人参皂苷所具有的抗糖尿病、抗癌、抗氧化和抗炎等生物特性使其尤为突出：本手稿全面探讨了人参在治疗各种癌症方面的多种应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current topics in medicinal chemistry 医学-医药化学

CiteScore

6.40

自引率

2.90%

发文量

186

审稿时长

3-8 weeks

期刊介绍： Current Topics in Medicinal Chemistry is a forum for the review of areas of keen and topical interest to medicinal chemists and others in the allied disciplines. Each issue is solely devoted to a specific topic, containing six to nine reviews, which provide the reader a comprehensive survey of that area. A Guest Editor who is an expert in the topic under review, will assemble each issue. The scope of Current Topics in Medicinal Chemistry will cover all areas of medicinal chemistry, including current developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, and structure-activity relationships. Medicinal chemistry is a rapidly maturing discipline. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. Current Topics in Medicinal Chemistry aims to contribute to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. The journal is essential for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important advances.