Insomnia, OSA, and Mood Disorders: The Gut Connection.

IF 5.5 2区医学 Q1 PSYCHIATRY

Current Psychiatry Reports Pub Date : 2024-10-14 DOI:10.1007/s11920-024-01546-9

André P Pacheco, Jonathan Cedernaes, Christian Benedict

引用次数: 0

Abstract

Purpose of review: With the growing body of research examining the link between sleep disorders, including insomnia and obstructive sleep apnea (OSA), and the gut microbiome, this review seeks to offer a thorough overview of the most significant findings in this emerging field.

Recent findings: Current evidence suggests a complex association between imbalances in the gut microbiome, insomnia, and OSA, with potential reciprocal interactions that may influence each other. Notably, specific gut microbiome species, whether over- or under-abundant, have been associated with variation in both sleep and mood in patients diagnosed with, e.g., major depressive disorder or bipolar disorder. Further studies are needed to explore the potential of targeting the gut microbiome as a therapeutic approach for insomnia and its possible effects on mood. The variability in current scientific literature highlights the importance of establishing standardized research methodologies.

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失眠、OSA 和情绪障碍：肠道联系

综述的目的：随着研究睡眠障碍（包括失眠和阻塞性睡眠呼吸暂停（OSA））与肠道微生物组之间联系的研究日益增多，本综述旨在对这一新兴领域最重要的发现进行全面概述：目前的证据表明，肠道微生物组失衡、失眠和 OSA 之间存在着复杂的联系，可能存在相互影响的相互作用。值得注意的是，特定的肠道微生物组物种，无论是过多还是过少，都与被诊断为重度抑郁症或躁郁症等患者的睡眠和情绪变化有关。还需要进一步的研究来探索针对肠道微生物组作为失眠症治疗方法的潜力及其对情绪可能产生的影响。目前科学文献中存在的差异凸显了建立标准化研究方法的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Psychiatry Reports PSYCHIATRY-

CiteScore

11.30

自引率

3.00%

发文量

审稿时长

6-12 weeks

期刊介绍： This journal aims to review the most important, recently published research in psychiatry. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care of those affected by psychiatric disorders. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as anxiety, medicopsychiatric disorders, and schizophrenia and other related psychotic disorders. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.