The effect of eccentric arm cycling on muscle damage and injury-related biomarkers.

IF 1.3 4区医学 Q4 PHYSIOLOGY

Clinical Physiology and Functional Imaging Pub Date : 2024-10-13 DOI:10.1111/cpf.12911

Frode Gottschalk, Mikael Gennser, Ola Eiken, Antonis Elia

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Abstract

Purpose: There is a scarcity of information regarding the effect of upper-body eccentric exercise on biomarkers of muscle damage. This study sought to investigate the effect of eccentric arm cycling on muscle damage [exercise-induced muscle damage (EIMD)].

Method: Ten subjects performed a 15 min eccentric arm cycling protocol (cadence 49 ± 7 rpm, power absorbed 248 ± 34 W). Maximal voluntary contraction (MVC) of the elbow flexors was evaluated at rest and at 5 min, 24 h, and 48 h post-exercise. In addition, blood samples were drawn at rest and thereafter at 30 min, 24 h, and 48 h intervals after exercise for quantification of creatine kinase (CK), myoglobin, lactate dehydrogenase (LDH) and endothelin (ET-1) concentrations. Delayed onset muscle soreness (DOMS) was assessed using a category ratio scale (0-10).

Results: Myoglobin was increased from baseline at 30 min post-exercise (+114%, 46.08 ± 22.17 µg/L, p = 0.018). Individual peak values were higher than baseline values for CK (+72.8%, 204 ± 138 U/L, p = 0.046) and LDH (+17%, 3.3 ± 0.88 nmole/min/mL, p = 0.017), but not for ET-1 (+9%, 1.4 ± 0.48 pg/mL, p = 0.45). DOMS was reported at 24 h (median 4) and 48 h (median 4) post-exercise and MVC of the elbow flexors were reduced from baseline (216 ± 44 N) at 5 min (-34%, 147 ± 61 N, p < 0.001), 24 h (-17%, 181 ± 56 N, p = 0.005) and 48 h (-9%, 191 ± 54 N, p = 0.003).

Conclusion: Eccentric arm cycling incites EIMD with reduced MVC and elevation of myoglobin, CK and LDH.

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手臂偏心骑行对肌肉损伤和损伤相关生物标志物的影响

目的：有关上半身偏心运动对肌肉损伤生物标志物的影响的信息很少。本研究旨在调查偏心臂骑行对肌肉损伤[运动诱发的肌肉损伤（EIMD）]的影响：方法：10 名受试者进行了 15 分钟的偏心手臂骑行（速度为 49 ± 7 rpm，吸收功率为 248 ± 34 W）。分别在休息时、运动后 5 分钟、24 小时和 48 小时评估肘部屈肌的最大自主收缩力（MVC）。此外，还在休息时和运动后 30 分钟、24 小时和 48 小时抽取血液样本，以量化肌酸激酶（CK）、肌红蛋白、乳酸脱氢酶（LDH）和内皮素（ET-1）的浓度。延迟性肌肉酸痛（DOMS）采用类别比率表（0-10）进行评估：结果：运动后 30 分钟肌红蛋白比基线高（+114%，46.08 ± 22.17 µg/L，p = 0.018）。CK（+72.8%，204 ± 138 U/L，p = 0.046）和 LDH（+17%，3.3 ± 0.88 nmole/min/mL，p = 0.017）的单项峰值高于基线值，但 ET-1（+9%，1.4 ± 0.48 pg/mL，p = 0.45）的单项峰值低于基线值。运动后 24 小时（中位数为 4）和 48 小时（中位数为 4）出现 DOMS，5 分钟时肘屈肌的 MVC 从基线（216 ± 44 N）降低（-34%，147 ± 61 N，p 结论：运动后 24 小时和 48 小时，肘屈肌的 MVC 从基线（216 ± 44 N）降低（-34%，147 ± 61 N，p）：偏心臂力自行车运动会诱发 EIMD，导致肌收缩力降低以及肌红蛋白、肌酸激酶和低密度脂蛋白胆固醇升高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Physiology and Functional Imaging 医学-生理学

CiteScore

3.40

自引率

5.60%

发文量

审稿时长

6-12 weeks

期刊介绍： Clinical Physiology and Functional Imaging publishes reports on clinical and experimental research pertinent to human physiology in health and disease. The scope of the Journal is very broad, covering all aspects of the regulatory system in the cardiovascular, renal and pulmonary systems with special emphasis on methodological aspects. The focus for the journal is, however, work that has potential clinical relevance. The Journal also features review articles on recent front-line research within these fields of interest. Covered by the major abstracting services including Current Contents and Science Citation Index, Clinical Physiology and Functional Imaging plays an important role in providing effective and productive communication among clinical physiologists world-wide.