Reductions in Chronic Postsurgical Neuropathic Pain and Mechanical Allodynia in Breast Cancer Patients Treated With Laser Acupuncture: A Retrospective Observational Study

IF 2.9 3区医学 Q2 ONCOLOGY

Clinical breast cancer Pub Date : 2024-09-20 DOI:10.1016/j.clbc.2024.09.005

Ian R.N. Relf , Tanishka Brahmanand

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引用次数: 0

Abstract

Introduction

Chronic postsurgical neuropathic pain (CPSNP) and related static mechanical allodynia (SMA) is recognised as a significant long-term complication after breast cancer surgery (BCS). This study investigates the effectiveness of a novel laser acupuncture technique in treating CPSNP and SMA post-BCS whilst patients underwent standard cancer treatments.

Methods

Thirty patients with significant breast area CPSNP and SMA (DN4 ≥ 4) were treated with 60Milliwatt, 658nm laser acupuncture at Austin Hospital between January 2021 and 2024. Patient data was analysed retrospectively: 29 with CPSNP, 22 with SMA. The cohort had exposures to pain aggravating cancer therapies (e.g. chemotherapy, radiotherapy and antihormonal medications). An online patient questionnaire assessed treatment outcomes qualitatively.

Results

Patients received an average of 6·4 treatments and their average CPSNP showed significant reduction from 6·86 to 1.29 (P < .001), with a mean 5.57 point decrease (95% CI, 4.90-6.24). Average SMA showed significant reduction from an average of 6.77-1.75 (P < .001), with a mean 5.02-point decrease (95% CI, 4.09-5.96). Pain reductions occurred despite NP aggravating treatment and ongoing usage by 40% of the cohort. 92% of patients reported acute reductions in SMA in the online questionnaire.

Conclusion

The significant pain reductions observed may indicate effectiveness of laser acupuncture in reducing both CPSNP and SMA in breast cancer patients post-BCS.

查看原文本刊更多论文

通过激光针灸减轻乳腺癌患者术后慢性神经病理性疼痛和机械性过敏：一项回顾性观察研究

导言：慢性手术后神经痛（CPSNP）和相关的静态机械异感（SMA）被认为是乳腺癌手术（BCS）后的一个重要的长期并发症。本研究调查了一种新型激光针灸技术在治疗乳腺癌术后CPSNP和SMA方面的效果，同时患者还接受了标准的癌症治疗：方法：2021 年 1 月至 2024 年期间，奥斯汀医院对 30 名乳腺区域 CPSNP 和 SMA（DN4 ≥ 4）明显的患者进行了 60 毫瓦、658 纳米激光针灸治疗。对患者数据进行了回顾性分析：29 人患有 CPSNP，22 人患有 SMA。患者均接受过加重疼痛的癌症疗法（如化疗、放疗和抗荷尔蒙药物）。一份在线患者问卷对治疗结果进行了定性评估：患者平均接受了 6-4 次治疗，其平均 CPSNP 从 6-86 显著降至 1.29（P < .001），平均下降了 5.57 点（95% CI，4.90-6.24）。平均 SMA 从平均 6.77-1.75 显著降低（P < .001），平均降低 5.02 分（95% CI，4.09-5.96）。40% 的患者在接受 NP 加重治疗和持续使用 NP 的情况下，疼痛仍有所减轻。92%的患者在在线问卷调查中表示SMA急性减轻：观察到的疼痛明显减轻可能表明，激光针灸在减轻乳腺癌患者 BCS 后的 CPSNP 和 SMA 方面都很有效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical breast cancer 医学-肿瘤学

CiteScore

5.40

自引率

3.20%

发文量

174

审稿时长

48 days

期刊介绍： Clinical Breast Cancer is a peer-reviewed bimonthly journal that publishes original articles describing various aspects of clinical and translational research of breast cancer. Clinical Breast Cancer is devoted to articles on detection, diagnosis, prevention, and treatment of breast cancer. The main emphasis is on recent scientific developments in all areas related to breast cancer. Specific areas of interest include clinical research reports from various therapeutic modalities, cancer genetics, drug sensitivity and resistance, novel imaging, tumor genomics, biomarkers, and chemoprevention strategies.