Recent Progress on NHC-Catalyzed 1,6-Conjugate Addition Reactions.

IF 7 2区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Chemical record Pub Date : 2024-11-01 Epub Date: 2024-10-17 DOI:10.1002/tcr.202400125

Jun Sun, Shichun Jiang, Yonggui Liu, Ling Pan, Ying-Guo Liu, Bing Zeng

引用次数: 0

Abstract

As a significant variant of the Michael reaction, the 1,6-addition reaction has undergone considerable development over the past decade. This effective strategy enables the synthesis of a variety of novel and potentially bioactive functional molecules. In this review, we summarize the recent progress in NHC-catalyzed 1,6-addition reactions, highlighting their efficiency in the rapid synthesis of complex functional molecules. We also provide our perspectives on the future development of this dynamic and highly active research area.

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NHC催化1,6-共轭物加成反应的最新进展。

作为迈克尔反应的一个重要变体，1,6-加成反应在过去十年中得到了长足的发展。这种有效的策略可以合成各种新型的、具有潜在生物活性的功能分子。在这篇综述中，我们总结了 NHC 催化的 1,6-加成反应的最新进展，强调了它们在快速合成复杂功能分子方面的效率。我们还对这一充满活力和高度活跃的研究领域的未来发展进行了展望。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemical record 化学-化学综合

CiteScore

11.00

自引率

3.00%

发文量

188

审稿时长

>12 weeks

期刊介绍： The Chemical Record (TCR) is a "highlights" journal publishing timely and critical overviews of new developments at the cutting edge of chemistry of interest to a wide audience of chemists (2013 journal impact factor: 5.577). The scope of published reviews includes all areas related to physical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, polymer chemistry, materials chemistry, bioorganic chemistry, biochemistry, biotechnology and medicinal chemistry as well as interdisciplinary fields. TCR provides carefully selected highlight papers by leading researchers that introduce the author''s own experimental and theoretical results in a framework designed to establish perspectives with earlier and contemporary work and provide a critical review of the present state of the subject. The articles are intended to present concise evaluations of current trends in chemistry research to help chemists gain useful insights into fields outside their specialization and provide experts with summaries of recent key developments.