The impact of season, environmental temperature and humidity on Raynaud phenomenon in an Australian systemic sclerosis cohort.

IF 3.7 2区医学 Q1 RHEUMATOLOGY

Arthritis Care & Research Pub Date : 2024-10-17 DOI:10.1002/acr.25452

Laura Taylor, Dylan Hansen, Kathleen Morrisroe, Jessica Fairley, Alicia Calderone, Shereen Oon, Laura Ross, Wendy Stevens, Nava Ferdowsi, Alannah Quinlivan, Joanne Sahhar, Gene-Siew Ngian, Diane Apostolopoulos, Lauren V Host, Jennifer Walker, Maryam Tabesh, Susanna Proudman, Mandana Nikpour

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引用次数: 0

Abstract

Objective: The aim of this study was to determine the impact of season, temperature and humidity on the severity of Raynaud phenomenon in systemic sclerosis.

Methods: Data from the Australian Scleroderma Cohort Study were utilised to assess associations of patient-reported worsened RP in the month preceding each study visit. Mean monthly weather data were obtained from the closest weather station to the patient's address. We evaluated the relationship between worsened RP and health-related quality of life (HRQoL) measured using the SF-36 instrument.

Results: Among 1972 systemic sclerosis patients, RP was a near universal finding, and worsened RP in the preceding month was reported in 26.7% of 9175 visits. 'Worsened RP' showed significant environmental variability. On multivariable analysis, worsened RP was associated with low mean maximum temperatures (OR 0.91, 95% CI 0.90-0.92, p<0.001), high relative humidity (OR 1.05, 95% CI 1.04-1.05, p<0.001 and lower mean daily evaporation (OR 0.77, 95% CI 0.73-0.81, p<0.001). Worsened RP was strongly associated with telangiectasia, calcinosis and digital ulceration (DU), as well as demonstrating an association with anti-centromere antibody and gastro-oesophageal reflux disease (GORD) and a negative correlation with diffuse disease. Worsened RP was also strongly associated with worse HRQoL.

Conclusion: Lower environmental temperature and higher relative humidity had significant associations with worsened RP in this systemic sclerosis cohort, suggesting an important role for dry warmth in managing this condition.

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季节、环境温度和湿度对澳大利亚系统性硬化症队列中雷诺现象的影响。

目的：本研究旨在确定季节、温度和湿度对系统性硬化症患者雷诺现象严重程度的影响：本研究旨在确定季节、温度和湿度对系统性硬化症患者雷诺现象严重程度的影响：方法：利用澳大利亚硬皮病队列研究（Australian Scleroderma Cohort Study）的数据，评估患者报告的雷诺现象恶化与每次就诊前一个月的相关性。每月平均天气数据来自距离患者住址最近的气象站。我们评估了RP恶化与使用SF-36工具测量的健康相关生活质量（HRQoL）之间的关系：结果：在 1972 名系统性硬化症患者中，RP 几乎是一个普遍发现，在 9175 次就诊中，有 26.7% 的患者在上个月报告 RP 恶化。RP 恶化 "显示出显著的环境变异性。在多变量分析中，RP恶化与平均最高气温低有关（OR 0.91，95% CI 0.90-0.92，p 结论：在这组系统性硬化症患者中，较低的环境温度和较高的相对湿度与 RP 恶化有显著相关性，这表明干暖疗法在控制病情方面发挥着重要作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Arthritis Care & Research RHEUMATOLOGY-

CiteScore

9.40

自引率

6.40%

发文量

368

审稿时长

3-6 weeks

期刊介绍： Arthritis Care & Research, an official journal of the American College of Rheumatology and the Association of Rheumatology Health Professionals (a division of the College), is a peer-reviewed publication that publishes original research, review articles, and editorials that promote excellence in the clinical practice of rheumatology. Relevant to the care of individuals with rheumatic diseases, major topics are evidence-based practice studies, clinical problems, practice guidelines, educational, social, and public health issues, health economics, health care policy, and future trends in rheumatology practice.