Carbon dots for pathogen detection and imaging: recent breakthroughs and future trends

IF 5.3 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchimica Acta Pub Date : 2024-10-21 DOI:10.1007/s00604-024-06762-x

Sonam Kumari, Monika Nehra, Shikha Jain, Aman Kumar, Neeraj Dilbaghi, Giovanna Marrazza, Ganga Ram Chaudhary, Sandeep Kumar

{"title":"Carbon dots for pathogen detection and imaging: recent breakthroughs and future trends","authors":"Sonam Kumari, Monika Nehra, Shikha Jain, Aman Kumar, Neeraj Dilbaghi, Giovanna Marrazza, Ganga Ram Chaudhary, Sandeep Kumar","doi":"10.1007/s00604-024-06762-x","DOIUrl":null,"url":null,"abstract":"<div><p>As a class of carbon-based nanomaterials, carbon dots (CDs) have gained a lot of interest for a variety of applications. They offer distinctive optical, chemical, and structural characteristics along with favourable attributes such as low cost, availability of abundant functional groups, remarkable chemical inertness, high stability, exceptional biocompatibility, and ecofriendliness. This review discusses synthesis methods, structural characteristics, and surface modifications of CDs, specific for pathogen detection. Furthermore, it delves into the mechanisms that govern the interaction between pathogens and CDs. In addition, the study explores the use of CDs in a number of detection modalities, such as optical, electrochemical, and electrochemiluminescence, emphasising real-time pathogen monitoring. Moreover, both the challenges and opportunities related to the application of CDs-based detection and imaging methods are highlighted in field and clinical contexts.</p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 11","pages":""},"PeriodicalIF":5.3000,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microchimica Acta","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s00604-024-06762-x","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}

引用次数: 0

Abstract

As a class of carbon-based nanomaterials, carbon dots (CDs) have gained a lot of interest for a variety of applications. They offer distinctive optical, chemical, and structural characteristics along with favourable attributes such as low cost, availability of abundant functional groups, remarkable chemical inertness, high stability, exceptional biocompatibility, and ecofriendliness. This review discusses synthesis methods, structural characteristics, and surface modifications of CDs, specific for pathogen detection. Furthermore, it delves into the mechanisms that govern the interaction between pathogens and CDs. In addition, the study explores the use of CDs in a number of detection modalities, such as optical, electrochemical, and electrochemiluminescence, emphasising real-time pathogen monitoring. Moreover, both the challenges and opportunities related to the application of CDs-based detection and imaging methods are highlighted in field and clinical contexts.

Graphical Abstract

查看原文本刊更多论文

用于病原体检测和成像的碳点：最新突破和未来趋势

作为一类碳基纳米材料，碳点（CD）在各种应用领域都受到了广泛关注。它们具有独特的光学、化学和结构特性，同时还具有低成本、丰富的官能团、显著的化学惰性、高稳定性、优异的生物相容性和生态友好性等有利特性。本综述讨论了 CD 的合成方法、结构特征和表面修饰，特别是用于病原体检测的方法。此外，它还深入探讨了病原体与光盘之间的相互作用机制。此外，该研究还探讨了 CD 在光学、电化学和电化学发光等多种检测模式中的应用，并强调了病原体的实时监测。此外，还强调了在现场和临床环境中应用基于光盘的检测和成像方法所面临的挑战和机遇。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Microchimica Acta 化学-分析化学

CiteScore

9.80

自引率

5.30%

发文量

410

审稿时长

2.7 months

期刊介绍： As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.