Nano-pesticide delivery system based on UiO-66 with pH sensitivity for precise control of Spodoptera frugiperda

IF 3.8 1区农林科学 Q1 AGRONOMY

Pest Management Science Pub Date : 2024-10-18 DOI:10.1002/ps.8483

Chaoqun Hou, Nuo Wei, Qianwei Liang, Yifei Tan, Xiang Li, Jianguo Feng

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Abstract

BACKGROUND

Metal–organic frameworks have the advantages of easy synthesis, high loading capacity and good biocompatibility, making them essential materials for constructing pesticide nano-delivery systems. In this study, a pH-responsive nano-controlled-release formulation Chl@UiO-66 was prepared using UiO-66 as the nano-scale carrier for adsorbing chlorantraniliprole (Chl).

RESULTS

The appearance, pesticide loading, release behaviour, insecticidal activity, long-term control efficacy and safety of Chl@UiO-66 for non-target organisms were extensively evaluated. The results showed that the prepared Chl@UiO-66 was a regular octahedron with a uniform particle size of 230 nm and pesticide loading of 15.62%. The release of pesticides under alkaline conditions was superior to that under acidic and neutral conditions, which showed pH-responsive performance. Chl@UiO-66 had an excellent ability to protect pesticides from ultraviolet degradation. Compared with chlorantraniliprole suspension concentrate, Chl@UiO-66 had a better control effect against Spodoptera frugiperda and long-term control efficacy. The prepared nano-controlled-release formulation had low toxicity to zebrafish, earthworms and human BEAS-2B cells.

CONCLUSION

Abstract Image

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基于 UiO-66 的纳米农药递送系统对 pH 值具有敏感性，可精确控制蚜虫。

背景金属有机框架具有易合成、高负载能力和良好的生物相容性等优点，是构建农药纳米释放系统的重要材料。结果广泛评价了 Chl@UiO-66 的外观、农药负载量、释放行为、杀虫活性、长期防治效果以及对非靶标生物的安全性。结果表明，制备的 Chl@UiO-66 为规则的八面体，粒径为 230 nm，农药负载量为 15.62%。在碱性条件下的农药释放量优于酸性和中性条件下的释放量，表现出良好的pH响应性能。Chl@UiO-66 对农药具有良好的紫外降解保护能力。与氯虫苯甲酰胺悬浮剂相比，Chl@UiO-66 对蚜虫具有更好的防治效果和长效性。制备的纳米控释制剂对斑马鱼、蚯蚓和人类 BEAS-2B 细胞毒性较低。© 2024 化学工业协会。

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来源期刊

Pest Management Science 农林科学-昆虫学

CiteScore

7.90

自引率

9.80%

发文量

553

审稿时长

4.8 months

期刊介绍： Pest Management Science is the international journal of research and development in crop protection and pest control. Since its launch in 1970, the journal has become the premier forum for papers on the discovery, application, and impact on the environment of products and strategies designed for pest management. Published for SCI by John Wiley & Sons Ltd.