Current status and perspectives in environmental oncology

Q1 Medicine
Jie Liu, Ting Gan, Wenbiao Hu, Yumin Li
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引用次数: 0

Abstract

Cancer stands as a leading global cause of death, with its etiology characterized by complexity and multifaceted factors. Growing research indicates a strong correlation between environmental factors and cancer incidence, underscoring the critical importance of intervening in environmental risk factors to mitigate cancer occurrence. Despite this, specialized research institutions focusing on the intersection of environment and cancer remain scarce, with global investment in cancer prevention significantly trailing behind efforts in diagnosis and treatment. Against the backdrop of rapid global climate change, industrialization, urbanization, aging populations, and the globalization of lifestyles, we proposed the concept of Environmental Oncology (EO) to address these challenges. We discussed the rationale and necessity of developing EO and presented a comprehensive research framework focusing on cancer prevention and treatment. Future EO research will aim to identify cancer causes and implement early prevention strategies using advanced scientific technologies and methods. By emphasizing multidisciplinary collaboration and integrating molecular biology at the micro level, EO will explore the relationship between external and internal environments and cancer. EO will identify potential therapeutic targets by studying the pathways through which environmental exposures lead to carcinogenesis. EO will develop early warning systems and disseminate research findings by collecting big data, employing robust statistical models, and establishing research centers.

Abstract Image

环境肿瘤学的现状和前景
癌症是全球主要死因之一,其病因具有复杂性和多面性。越来越多的研究表明,环境因素与癌症发病率之间存在着密切的相关性,这凸显了干预环境风险因素以减少癌症发生的极端重要性。尽管如此,专注于环境与癌症交叉问题的专业研究机构仍然很少,全球在癌症预防方面的投资明显落后于诊断和治疗方面的投资。在全球气候变化迅速、工业化、城市化、人口老龄化和生活方式全球化的背景下,我们提出了环境肿瘤学(EO)的概念来应对这些挑战。我们讨论了发展环境肿瘤学的理由和必要性,并提出了以癌症预防和治疗为重点的综合研究框架。未来的环境肿瘤学研究将致力于利用先进的科学技术和方法找出癌症的成因并实施早期预防策略。通过强调多学科合作和在微观层面整合分子生物学,EO 将探索外部和内部环境与癌症之间的关系。EO 将通过研究环境暴露导致致癌的途径来确定潜在的治疗目标。EO 将通过收集大数据、采用强大的统计模型和建立研究中心来开发预警系统和传播研究成果。
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来源期刊
CiteScore
6.70
自引率
0.00%
发文量
195
审稿时长
35 weeks
期刊介绍: This journal aims to promote progress from basic research to clinical practice and to provide a forum for communication among basic, translational, and clinical research practitioners and physicians from all relevant disciplines. Chronic diseases such as cardiovascular diseases, cancer, diabetes, stroke, chronic respiratory diseases (such as asthma and COPD), chronic kidney diseases, and related translational research. Topics of interest for Chronic Diseases and Translational Medicine include Research and commentary on models of chronic diseases with significant implications for disease diagnosis and treatment Investigative studies of human biology with an emphasis on disease Perspectives and reviews on research topics that discuss the implications of findings from the viewpoints of basic science and clinical practic.
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