Pediatric COVID-19 vaccine hesitancy among pregnant and post-partum women: A mixed-method study

IF 4.5 3区医学 Q2 IMMUNOLOGY

Vaccine Pub Date : 2024-10-16 DOI:10.1016/j.vaccine.2024.126420

Tasmiah Nuzhath , Brian Colwell , Timothy Callaghan , Peter Hotez , Sabrina Mousum , Ummul Wara Masud , Annette K. Regan

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引用次数: 0

Abstract

Background

This study aims to understand factors contributing to pediatric COVID-19 vaccine hesitancy among pregnant and postpartum adults.

Method

The study used targeted intercept advertising on Facebook, Twitter, and Instagram to recruit a panel of 3600 pregnant and postpartum US adults. Data were collected between December 2021 and April 2022 (i.e., before the introduction of pediatric COVID-19 vaccines in the U.S.). We used logistic regression to understand factors associated with pregnant and postpartum women's hesitancy towards getting children <5 vaccinated against COVID-19. Poststratification weights were applied to analyses to promote the representativeness of the sample. We also conducted a qualitative thematic analysis to determine the reasons for pediatric vaccine hesitancy.

Results

Nearly half (45.6 %) of pregnant or postpartum women were hesitant to vaccinate their child against COVID-19. Vaccine hesitancy was lower among those who had a high perceived susceptibility to COVID-19, had increased perceived severity of COVID-19, and increased perceived benefits of the COVID-19 vaccine. Perceived barriers related to long-term side effects of vaccines were positively associated with hesitancy to vaccinate children. Older women, women in urban areas, and those born outside the US were less likely to be hesitant to vaccinate children <5 against COVID-19. Compared to respondents with a high school education or less, the odds of pediatric vaccine hesitancy were higher among respondents with some college. Pregnant and postpartum women who were hesitant about getting children <5 vaccinated cited the following reasons for hesitancy: concerns about the vaccine, lack of evidence on vaccine safety, and the COVID-19 vaccine is not necessary for children.

Conclusion

Our findings suggest that public health messages to promote the COVID-19 vaccine for young children should focus on the risks and consequences of the disease and share data on the effectiveness of the vaccine in preventing severe COVID-19-related outcomes.

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孕妇和产后妇女对小儿 COVID-19 疫苗的犹豫不决：混合方法研究

背景本研究旨在了解导致孕妇和产后成人对小儿 COVID-19 疫苗犹豫不决的因素。方法本研究利用 Facebook、Twitter 和 Instagram 上的定向拦截广告招募了 3600 名美国孕妇和产后成人。数据收集时间为 2021 年 12 月至 2022 年 4 月（即美国引入小儿 COVID-19 疫苗之前）。我们采用逻辑回归的方法来了解孕妇和产后妇女对让孩子接种 COVID-19 疫苗犹豫不决的相关因素。为了提高样本的代表性，我们对分析进行了后分层加权。我们还进行了定性专题分析，以确定儿科疫苗接种犹豫不决的原因。结果近一半（45.6%）的孕妇或产后妇女对是否为其子女接种 COVID-19 疫苗犹豫不决。对 COVID-19 的易感性高、对 COVID-19 的严重性认知度高以及对 COVID-19 疫苗的益处认知度高的妇女犹豫接种的比例较低。与疫苗长期副作用相关的认知障碍与儿童接种犹豫呈正相关。年龄较大的女性、城市地区的女性以及在美国以外出生的女性不太可能对儿童接种 COVID-19 疫苗犹豫不决。与高中或高中以下学历的受访者相比，受过一定教育的受访者对儿童疫苗接种犹豫不决的几率更高。对儿童接种COVID-19疫苗犹豫不决的孕妇和产后妇女提出了以下犹豫不决的原因：对疫苗的担忧、缺乏疫苗安全性的证据以及儿童没有必要接种COVID-19疫苗。结论我们的研究结果表明，推广幼儿接种COVID-19疫苗的公共卫生信息应侧重于该疾病的风险和后果，并分享疫苗在预防与COVID-19相关的严重后果方面的有效性数据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Vaccine 医学-免疫学

CiteScore

8.70

自引率

5.50%

发文量

992

审稿时长

131 days

期刊介绍： Vaccine is unique in publishing the highest quality science across all disciplines relevant to the field of vaccinology - all original article submissions across basic and clinical research, vaccine manufacturing, history, public policy, behavioral science and ethics, social sciences, safety, and many other related areas are welcomed. The submission categories as given in the Guide for Authors indicate where we receive the most papers. Papers outside these major areas are also welcome and authors are encouraged to contact us with specific questions.