Recent advances and principles of metal–organic framework for the detection of chloramphenicol: Perspectives and challenges

IF 4.9 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchemical Journal Pub Date : 2024-10-10 DOI:10.1016/j.microc.2024.111878

Miao Liu , Kayhaneh Berijani , Jiaxin Ma , Sirui Guo , Yanqiong Peng , Ying Pan , Ali Morsali , Yong Huang

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Abstract

According to the continuous development of today’s society, the production of environmental pollutants has been a severe concern observed in the drug industries. For instance, the demand for the consumption of antibiotics is one of them that is increasing, and the residual hazards of the broad-spectrum antibiotic chloramphenicol (CAP) are widespread, which can not only pollute the environment but can also have negative health impacts on humans. Thus, the detection of CAP is of great significance. Among the used chemical materials to solve this issue, the essential metal–organic skeletons, namely metal–organic frameworks (MOFs) have promising applications due to their advantages such as large specific surface area (SA), abundant pores, and luminescent properties. This paper describes the principles of electrochemical, fluorescent, and probe assays related to the detection of CAP. A more comprehensive overview of the use of MOFs for the detection of CAP and other antibiotics in water and food and how CAP can be monitored with high sensitivity, high selectivity, and stability in the form of various sensors is given, as well as future perspectives on MOFs materials that have the potential to be used as sensors.

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用于检测氯霉素的金属有机框架的最新进展和原理：前景与挑战

随着当今社会的不断发展，环境污染物的产生已成为药品行业严重关注的问题。例如，人们对抗生素的消费需求与日俱增，而广谱抗生素氯霉素（CAP）的残留危害十分普遍，不仅会污染环境，还会对人体健康产生负面影响。因此，CAP 的检测意义重大。在用于解决这一问题的化学材料中，重要的金属有机骨架，即金属有机框架（MOFs）因其具有大比表面积（SA）、丰富的孔隙和发光特性等优点而具有广阔的应用前景。本文介绍了与检测 CAP 相关的电化学、荧光和探针测定原理。本文更全面地概述了如何利用 MOFs 检测水和食品中的 CAP 及其他抗生素，以及如何以各种传感器的形式高灵敏度、高选择性和高稳定性地监测 CAP，并展望了有可能用作传感器的 MOFs 材料的未来前景。

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来源期刊

Microchemical Journal 化学-分析化学

CiteScore

8.70

自引率

8.30%

发文量

1131

审稿时长

1.9 months

期刊介绍： The Microchemical Journal is a peer reviewed journal devoted to all aspects and phases of analytical chemistry and chemical analysis. The Microchemical Journal publishes articles which are at the forefront of modern analytical chemistry and cover innovations in the techniques to the finest possible limits. This includes fundamental aspects, instrumentation, new developments, innovative and novel methods and applications including environmental and clinical field. Traditional classical analytical methods such as spectrophotometry and titrimetry as well as established instrumentation methods such as flame and graphite furnace atomic absorption spectrometry, gas chromatography, and modified glassy or carbon electrode electrochemical methods will be considered, provided they show significant improvements and novelty compared to the established methods.