Undetectable pre-radical cystectomy circulating tumour DNA status predicts improved oncological outcomes

IF 3.7 2区医学 Q1 UROLOGY & NEPHROLOGY

BJU International Pub Date : 2024-10-16 DOI:10.1111/bju.16556

Reuben Ben-David, Sarah Lidagoster, Jack Geduldig, Kaushik P. Kolanukuduru, Yuval Elkun, Neeraja Tillu, Asher Mandel, Mohammed Almoflihi, Basil Kaufmann, Kyrollis Attalla, Reza Mehrazin, Peter Wiklund, John P. Sfakianos

引用次数: 0

Abstract

To assess recurrence-free survival (RFS) in patients with undetectable tumour-informed circulating tumour DNA (ctDNA) before radical cystectomy (RC) and evaluate if those who converted from detectable to undetectable ctDNA status after RC have similar RFS outcomes as those with persistently undetectable ctDNA status.

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根治性膀胱切除术前检测不到循环肿瘤 DNA 状态可预示肿瘤治疗效果的改善

目的：评估根治性膀胱切除术（RC）前检测不到肿瘤信息循环肿瘤DNA（ctDNA）的患者的无复发生存期（RFS），并评估RC后从检测到ctDNA转为检测不到的患者是否与持续检测不到ctDNA的患者具有相似的RFS结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BJU International 医学-泌尿学与肾脏学

CiteScore

9.10

自引率

4.40%

发文量

262

审稿时长

1 months

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