Fabricating Biodegradable Tissue Scaffolds Through a New Aggregation Triggered Physical Cross-Linking Strategy of Hydrophilic and Hydrophobic Polymers

Abstract

Front Cover: Taking the advantage of hydrophobic nature of PLGA and branched structure of POEGMEMA, enables to get physically cross-linked scaffolds. Physical cross-linking is achieved by aggregation of PLGA in aqueous media and formation of intra- and inter-molecular entangles between aggregated PLGA and branched POEGMEMA polymers. Thus, though high hydrophilic POEGMEMA content, robust polymeric scaffolds are obtained without using toxic reactions. More details can be found in article 2400112 by Elif Kaga and Sadik Kaga.