Structure-based virtual screening of novel chitin synthase inhibitors for the control of Phytophthora sojae

IF 3.8 1区农林科学 Q1 AGRONOMY

Pest Management Science Pub Date : 2024-10-15 DOI:10.1002/ps.8480

Yuansheng Liu, Jinfeng Liu, Yeqiang Xia, Wei Chen, Yingchen Li, Xiao He, Qing Yang

引用次数: 0

Abstract

Chitin synthase (CHS) is an important target for pesticide development as chitin biosynthesis is essential for the survival and reproduction of various organisms, such as oomycetes, fungi and insects. Small-molecule inhibitors of CHS have potential applications for the control of agricultural pests and diseases.

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基于结构的虚拟筛选新型几丁质合成酶抑制剂，用于防治根腐病

几丁质合成酶（CHS）是农药开发的一个重要目标，因为几丁质的生物合成对卵菌、真菌和昆虫等各种生物的生存和繁殖至关重要。几丁质酶的小分子抑制剂具有防治农业病虫害的潜在用途。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pest Management Science 农林科学-昆虫学

CiteScore

7.90

自引率

9.80%

发文量

553

审稿时长

4.8 months

期刊介绍： Pest Management Science is the international journal of research and development in crop protection and pest control. Since its launch in 1970, the journal has become the premier forum for papers on the discovery, application, and impact on the environment of products and strategies designed for pest management. Published for SCI by John Wiley & Sons Ltd.