New triazole-containing 7-azacoumarin-3-carboxamides: synthesis and biological properties

IF 1.8 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Mendeleev Communications Pub Date : 2024-09-01 DOI:10.1016/j.mencom.2024.09.020

Alexey V. Trifonov, Roza K. Bagautdinova, Lyudmila K. Kibardina, Michail A. Pudovik, Anna P. Lyubina, Alexandra D. Voloshina, Almir S. Gazizov, Alexander R. Burilov

引用次数: 0

Abstract

New azidomethyl-substituted 7-azacoumarin-3-carbox- amides were converted into the corresponding 1,2,3-triazole hybrids by the copper-catalyzed click reaction with phenyl- acetylene. Cytotoxicity and antimicrobial activity were evaluated, and leading compounds were identified.

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新的含三唑的 7-氮杂香豆素-3-羧酰胺：合成与生物特性

通过铜催化与苯基乙炔的点击反应，将新的叠氮甲基取代的 7-氮杂香豆素-3-甲酰胺转化为相应的 1,2,3-三唑杂化物。对其细胞毒性和抗菌活性进行了评估，并确定了主要化合物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Mendeleev Communications 化学-化学综合

CiteScore

3.00

自引率

21.10%

发文量

226

审稿时长

4-8 weeks

期刊介绍： Mendeleev Communications is the journal of the Russian Academy of Sciences, launched jointly by the Academy of Sciences of the USSR and the Royal Society of Chemistry (United Kingdom) in 1991. Starting from 1st January 2007, Elsevier is the new publishing partner of Mendeleev Communications. Mendeleev Communications publishes short communications in chemistry. The journal primarily features papers from the Russian Federation and the other states of the former USSR. However, it also includes papers by authors from other parts of the world. Mendeleev Communications is not a translated journal, but instead is published directly in English. The International Editorial Board is composed of eminent scientists who provide advice on refereeing policy.