Knowing when to stop: MICL self-regulates neutrophil NETosis

IF 28.1 1区生物学 Q1 CELL BIOLOGY

Cell Research Pub Date : 2024-10-14 DOI:10.1038/s41422-024-01037-9

Hanjoo Brian Shim, Justin François Deniset, Paul Kubes

引用次数: 0

Abstract

In a recent study published in Nature, Malamud et al. identified how neutrophil MICL recognizes neutrophil extracellular traps (NETs). This recognition suppresses further neutrophil activation and NET production, thereby preventing a vicious cycle of inflammation.

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知道何时停止：MICL 自我调节中性粒细胞 NETosis

在最近发表于《自然》（Nature）的一项研究中，Malamud 等人确定了中性粒细胞 MICL 如何识别中性粒细胞胞外捕获物（NET）。这种识别抑制了中性粒细胞的进一步活化和 NET 的产生，从而防止了炎症的恶性循环。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell Research 生物-细胞生物学

CiteScore

53.90

自引率

0.70%

发文量

2420

审稿时长

2.3 months

期刊介绍： Cell Research (CR) is an international journal published by Springer Nature in partnership with the Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CAS). It focuses on publishing original research articles and reviews in various areas of life sciences, particularly those related to molecular and cell biology. The journal covers a broad range of topics including cell growth, differentiation, and apoptosis; signal transduction; stem cell biology and development; chromatin, epigenetics, and transcription; RNA biology; structural and molecular biology; cancer biology and metabolism; immunity and molecular pathogenesis; molecular and cellular neuroscience; plant molecular and cell biology; and omics, system biology, and synthetic biology. CR is recognized as China's best international journal in life sciences and is part of Springer Nature's prestigious family of Molecular Cell Biology journals.