Facile two step approach of Chitosan/Nickel/ZrO2 bio-nanocomposite and investigation of their antimicrobial activities against Escherichia coli

IF 3.2 4区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Journal of the Indian Chemical Society Pub Date : 2024-09-26 DOI:10.1016/j.jics.2024.101392

{"title":"Facile two step approach of Chitosan/Nickel/ZrO2 bio-nanocomposite and investigation of their antimicrobial activities against Escherichia coli","authors":"","doi":"10.1016/j.jics.2024.101392","DOIUrl":null,"url":null,"abstract":"<div><div>Chitosan nanoparticles (CH NPs), ZrO2, Ni/ZrO2. CH/ZrO2 and CH/Ni/ZrO2 complex have been synthesized then its antibacterial mechanisms of nanomaterials against Escherichia coli (E. coli) was evaluated by agar well diffusion and systematically analyzed by measuring the diameter of the inhibition zone. X-ray diffraction (XRD) patterns and Fourier transform infrared (FTIR) spectra and Energy dispersive X-ray (EDX) results demonstrated the formation of CH/Ni/ZrO2 matrix. Also, the crystalline sizes were found to be 15, 13, 10 and 8 nm for ZrO2, Ni/ZrO2, CH/ZrO2 and CH/Ni/ZrO2 respectively. The FTIR spectrum revealed bands ranging from 400 to 800 cm−1, indicating the presence of metal–oxygen bonds. Additionally, bands at 1620, 1523, and 1300 cm−1 suggested the presence of amide groups, confirming the presence of CH in the produced CH/Ni/ZrO2 nanocomposite. In SEM analysis, the irregular spherical nanoparticles are observed in case ZrO2 and CH/ZrO2 samples, while spherical with an oval-shaped structure are observed in case of Ni/ZrO2 and CH/Ni/ZrO2 sample. Mean diameter of inhibition zone were observed to be 13 ± 2.51, 12 ± 2.08, 16 ± 1.3 mm,17 ± 2.3 mm and 18 ± 0.8 nm for CH, ZrO2, Ni/ZrO2, CH/ZrO2 and CH/Ni/ZrO2 respectively. The eco-friendly and cost-effective synthesis of Chitosan assisted Ni/ZrO2 NPs can be utilized as an effective antibacterial agent.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":null,"pages":null},"PeriodicalIF":3.2000,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Indian Chemical Society","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0019452224002723","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

Chitosan nanoparticles (CH NPs), ZrO₂, Ni/ZrO₂. CH/ZrO₂ and CH/Ni/ZrO₂ complex have been synthesized then its antibacterial mechanisms of nanomaterials against Escherichia coli (E. coli) was evaluated by agar well diffusion and systematically analyzed by measuring the diameter of the inhibition zone. X-ray diffraction (XRD) patterns and Fourier transform infrared (FTIR) spectra and Energy dispersive X-ray (EDX) results demonstrated the formation of CH/Ni/ZrO₂ matrix. Also, the crystalline sizes were found to be 15, 13, 10 and 8 nm for ZrO₂, Ni/ZrO₂, CH/ZrO₂ and CH/Ni/ZrO₂ respectively. The FTIR spectrum revealed bands ranging from 400 to 800 cm⁻¹, indicating the presence of metal–oxygen bonds. Additionally, bands at 1620, 1523, and 1300 cm⁻¹ suggested the presence of amide groups, confirming the presence of CH in the produced CH/Ni/ZrO2 nanocomposite. In SEM analysis, the irregular spherical nanoparticles are observed in case ZrO₂ and CH/ZrO₂ samples, while spherical with an oval-shaped structure are observed in case of Ni/ZrO₂ and CH/Ni/ZrO₂ sample. Mean diameter of inhibition zone were observed to be 13 ± 2.51, 12 ± 2.08, 16 ± 1.3 mm,17 ± 2.3 mm and 18 ± 0.8 nm for CH, ZrO₂, Ni/ZrO₂, CH/ZrO₂ and CH/Ni/ZrO₂ respectively. The eco-friendly and cost-effective synthesis of Chitosan assisted Ni/ZrO₂ NPs can be utilized as an effective antibacterial agent.

Abstract Image

查看原文本刊更多论文

壳聚糖/镍/二氧化锆生物纳米复合材料的简便两步法及其对大肠杆菌抗菌活性的研究

研究人员合成了壳聚糖纳米粒子（CH NPs）、ZrO2、Ni/ZrO2、CH/ZrO2 和 CH/Ni/ZrO2 复合物。合成了 CH/ZrO2 和 CH/Ni/ZrO2 复合物，然后用琼脂井扩散法评估了纳米材料对大肠杆菌（E. coli）的抗菌机制，并通过测量抑菌区的直径进行了系统分析。X 射线衍射（XRD）图谱、傅立叶变换红外（FTIR）光谱和能量色散 X 射线（EDX）结果表明形成了 CH/Ni/ZrO2 基体。此外，ZrO2、Ni/ZrO2、CH/ZrO2 和 CH/Ni/ZrO2 的结晶尺寸分别为 15、13、10 和 8 纳米。傅立叶变换红外光谱显示了 400 至 800 cm-1 的频带，表明存在金属氧键。此外，1620、1523 和 1300 cm-1 处的谱带表明存在酰胺基团，从而证实了 CH/Ni/ZrO2 纳米复合材料中存在 CH。在扫描电镜分析中，ZrO2 和 CH/ZrO2 样品观察到不规则的球形纳米颗粒，而 Ni/ZrO2 和 CH/Ni/ZrO2 样品观察到椭圆形的球形结构。CH、ZrO2、Ni/ZrO2、CH/ZrO2 和 CH/Ni/ZrO2 的抑制区平均直径分别为 13 ± 2.51、12 ± 2.08、16 ± 1.3 mm、17 ± 2.3 mm 和 18 ± 0.8 nm。壳聚糖辅助 Ni/ZrO2 NPs 的合成既环保又经济，可用作有效的抗菌剂。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of the Indian Chemical Society 化学-化学综合

CiteScore

3.50

自引率

7.70%

发文量

492

审稿时长

3-8 weeks

期刊介绍： The Journal of the Indian Chemical Society publishes original, fundamental, theorical, experimental research work of highest quality in all areas of chemistry, biochemistry, medicinal chemistry, electrochemistry, agrochemistry, chemical engineering and technology, food chemistry, environmental chemistry, etc.