Protocolo diagnóstico diferencial de otras diabetes diagnosticadas en la juventud

Abstract

This protocol focuses on the differential diagnosis of type 1 diabetes mellitus (DM1) in young patients, emphasizing that though DM1 is the most common form of diabetes in this population, other forms of diabetes, such as type 2 diabetes (DM2) and monogenic diabetes, should be considered. The diagnostic process entails differentiation between DM1; DM2; and other rare forms such as monogenic diabetes, diabetes of the exocrine pancreas, or drug-induced diabetes. Clinical factors and findings, such as negativity for pancreatic autoimmunity, body mass index (BMI), and family history, are described in order to help differentiate these conditions. A diagnostic algorithm is included to guide the clinical evaluation and the importance of performing genetic studies in suspected cases of monogenic diabetes is described. This protocol highlights the importance of a comprehensive evaluation to ensure an accurate diagnosis in young patients with diabetes.