Adult nephroblastoma or Wilms' tumor: A rare entity - Case report

Abstract

Wilms' tumor (nephroblastoma) is rare in adults, comprising less than 5 % of renal cancers. This report details a 48-year-old male with persistent abdominal pain, weight loss, and fatigue, whose imaging showed a large, heterogeneous left renal mass with regional lymph node involvement. Post-nephrectomy histology confirmed nephroblastoma with a triphasic pattern. The patient underwent left radical nephrectomy and received adjuvant chemotherapy with doxorubicin, vincristine, and actinomycin D. Three months later, follow-up CT scans revealed no residual disease. This case underscores the diagnostic and therapeutic challenges of adult nephroblastoma and the need for more effective treatment protocols.