G.B. John Mancini MD , Glen J. Pearson PharmD, FCSHP, FCCS , Arden R. Barry PharmD , Patrick Couture MD, FRCP(C), PhD , Natalie Dayan MD, MSc , Gordon A. Francis MD , Jacques Genest MD , Jean C. Gregoire MD , Robert A. Hegele MD, PhD , Lawrence A. Leiter MD , Alexander A. Leung MD, MPH , Eva Lonn MD, MSc , Priya Manjoo MD, MSc , Daniel Ngui MD , Marie-Eve Piché MD, PhD , Paul Poirier MD, PhD , John L. Sievenpiper MD, PhD , George Thanassoulis MD , Richard Ward MD
{"title":"Prevention and Management of Cardiovascular Disease in Primary Care: A Comment on the PEER Simplified Lipid Guideline","authors":"G.B. John Mancini MD , Glen J. Pearson PharmD, FCSHP, FCCS , Arden R. Barry PharmD , Patrick Couture MD, FRCP(C), PhD , Natalie Dayan MD, MSc , Gordon A. Francis MD , Jacques Genest MD , Jean C. Gregoire MD , Robert A. Hegele MD, PhD , Lawrence A. Leiter MD , Alexander A. Leung MD, MPH , Eva Lonn MD, MSc , Priya Manjoo MD, MSc , Daniel Ngui MD , Marie-Eve Piché MD, PhD , Paul Poirier MD, PhD , John L. Sievenpiper MD, PhD , George Thanassoulis MD , Richard Ward MD","doi":"10.1016/j.cjco.2024.06.006","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>In Canada, 2 guidelines provide guidance for the management of dyslipidemia. The Patients, Experience, Evidence, Research simplified lipid guidelines, intended for primary care practitioners, and the Canadian Cardiovascular Society guidelines, intended for all practitioners, are based on differing methodologies with distinct priorities and preferences. The disparate approaches may contribute to confusion among family practitioners and their co-managed patients, with the potential for compromised care, differing standards for training in the fundamentals of lipidology, and differing criteria that might be used in practice audits to evaluate quality of care.</div></div><div><h3>Methods</h3><div>The Patients, Experience, Evidence, Research (PEER) recommendations were considered by primary authors of the Canadian Cardiovascular Society guideline to identify areas of concordance, discordance, or agreement with qualifications.</div></div><div><h3>Results</h3><div>Discordance between the guidelines is greatest with respect to interpretation of the cholesterol profile, the implications of elevated triglyceride, the utility of apolipoprotein B and non-high-density lipoprotein-cholesterol measurements, the role of nonstatin medications, and the importance of assuring adherence and avoiding undertreatment through follow-up measurement of lipid profiles. The disparate importance attached to identification of patients with enhanced risk due to an elevated lipoprotein (a) level is also apparent.</div></div><div><h3>Conclusions</h3><div>This comparison attempts to reconcile key principles of practice, to foster both high quality of care and fully informed patient-centred decision-making.</div></div>","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":"6 10","pages":"Pages 1189-1198"},"PeriodicalIF":2.5000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"CJC Open","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2589790X24002567","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Background
In Canada, 2 guidelines provide guidance for the management of dyslipidemia. The Patients, Experience, Evidence, Research simplified lipid guidelines, intended for primary care practitioners, and the Canadian Cardiovascular Society guidelines, intended for all practitioners, are based on differing methodologies with distinct priorities and preferences. The disparate approaches may contribute to confusion among family practitioners and their co-managed patients, with the potential for compromised care, differing standards for training in the fundamentals of lipidology, and differing criteria that might be used in practice audits to evaluate quality of care.
Methods
The Patients, Experience, Evidence, Research (PEER) recommendations were considered by primary authors of the Canadian Cardiovascular Society guideline to identify areas of concordance, discordance, or agreement with qualifications.
Results
Discordance between the guidelines is greatest with respect to interpretation of the cholesterol profile, the implications of elevated triglyceride, the utility of apolipoprotein B and non-high-density lipoprotein-cholesterol measurements, the role of nonstatin medications, and the importance of assuring adherence and avoiding undertreatment through follow-up measurement of lipid profiles. The disparate importance attached to identification of patients with enhanced risk due to an elevated lipoprotein (a) level is also apparent.
Conclusions
This comparison attempts to reconcile key principles of practice, to foster both high quality of care and fully informed patient-centred decision-making.
背景在加拿大,有两份指南为血脂异常的管理提供指导。患者、经验、证据、研究 "简化血脂指南适用于初级保健从业人员,而加拿大心血管协会指南适用于所有从业人员。方法加拿大心血管协会指南的主要作者考虑了患者、经验、证据、研究(PEER)的建议,以确定一致、不一致或与资格一致的领域。结果指南之间最不一致的地方是对胆固醇谱的解释、甘油三酯升高的影响、载脂蛋白 B 和非高密度脂蛋白胆固醇测量的效用、非他汀类药物的作用以及通过血脂谱随访测量确保坚持治疗和避免治疗不足的重要性。结论 本次比较试图协调实践中的主要原则,以促进高质量的护理和以患者为中心的充分知情决策。