A field comparison study of two vaccine protocols against Erysipelothrix rhusiopathiae in two types of swine breeds in Spain.

IF 2.3 2区 农林科学 Q1 VETERINARY SCIENCES
E Sanchez-Tarifa, C Alonso, I Perez, L A García, A Fernández-Fontelo, O Gómez-Duran, B García-Morante, Francisco A García-Vázquez, I Hernández-Caravaca
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Abstract

Erysipelas still causes large economic losses to pig industry. Maternal immunity is critical to prevent erysipelas in young animals, thus, intensive vaccination protocols or practices focused on the improvement of the maternally derived immunity could provide substantial benefits. The present study evaluates potential changes in antibodies levels in sows and their offspring using two types of tests (commercial ELISA, Ingenasa or rSpaA415 ELISA) when two different vaccination programs (before farrowing or after farrowing) against Erysipelothrix rhusiopathiae were applied to sows from Iberian (A) or conventional Large White-Landrace (B) pig farms. The results showed a statistical correlation between titers found in sows and their one-week old piglets in both tests. The overall mean of (log) antibody titers in farm B measured by the commercial ELISA test was significantly higher in pre-farrowing vaccinated sows compared to the post-farrowing vaccine protocol (p = 0.0278). Additionally, using the rSpaA415 ELISA test, the overall mean of (log) antibody titers was significantly higher in pre-farrowing sows (p = 0.0056) compared to sows following post-farrowing vaccine protocol (p = 0.0003) or non- vaccinated sows. None of the above-mentioned differences were found in farm A. The overall mean of (log) antibody titers in piglets from the pre-farrowing vaccination protocol was significantly higher than piglets from the post-farrowing vaccination protocol in farm A (p = 0.0059; rSpaA415 ELISA) and farm B (p = 0.0168 and p = 0.0098 for the commercial and rSpaA415 ELISA data, respectively). Additionally, higher proportion of piglets from pre-farrowing vaccinated sows remained seropositive during the post-weaning period (days 42 to 84) compared to piglets from non-vaccinated or post-farrowing vaccinated groups in both farms A and B.

在西班牙两种猪种中对两种预防红腹泻温热病疫苗方案进行实地比较研究。
红臀疽仍然给养猪业造成巨大的经济损失。母源免疫对预防幼畜红痢至关重要,因此,强化疫苗接种方案或以提高母源免疫力为重点的做法可带来巨大收益。本研究使用两种检测方法(商业 ELISA、Ingenasa 或 rSpaA415 ELISA)评估了伊比利亚猪场(A)或传统大白兰氏猪场(B)的母猪在接种两种不同的红细胞体病疫苗方案(产仔前或产仔后)时,母猪及其后代体内抗体水平的潜在变化。结果显示,在这两项试验中,母猪及其一周龄仔猪的抗体滴度之间存在统计学相关性。在 B 猪场,通过商业 ELISA 试验测定的抗体滴度(对数)的总体平均值在排卵前接种疫苗的母猪中明显高于排卵后接种疫苗的母猪(p = 0.0278)。此外,使用 rSpaA415 酶联免疫吸附试验(ELISA),与接种后疫苗的母猪(p = 0.0003)或未接种疫苗的母猪相比,配种前母猪的抗体滴度(对数)总平均值明显更高(p = 0.0056)。在 A 猪场(p = 0.0059;rSpaA415 ELISA)和 B 猪场(商业数据和 rSpaA415 ELISA 数据分别为 p = 0.0168 和 p = 0.0098),排卵前接种方案的仔猪抗体滴度(对数)总平均值显著高于排卵后接种方案的仔猪。此外,在 A 猪场和 B 猪场,与未接种疫苗或接种疫苗后的仔猪相比,断奶前接种疫苗的母猪所产仔猪在断奶后(第 42 天至第 84 天)血清仍呈阳性的比例更高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMC Veterinary Research
BMC Veterinary Research VETERINARY SCIENCES-
CiteScore
4.80
自引率
3.80%
发文量
420
审稿时长
3-6 weeks
期刊介绍: BMC Veterinary Research is an open access, peer-reviewed journal that considers articles on all aspects of veterinary science and medicine, including the epidemiology, diagnosis, prevention and treatment of medical conditions of domestic, companion, farm and wild animals, as well as the biomedical processes that underlie their health.
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