RAMEZ BARBARA , AHMED M. ABDELAAL , REBECCA LEVY , ANITA NAGY , KAMIAR MIRESKANDARI , ASIM ALI
{"title":"Pediatric Eyelid Cutaneous Horns: A Case Series and Literature Review","authors":"RAMEZ BARBARA , AHMED M. ABDELAAL , REBECCA LEVY , ANITA NAGY , KAMIAR MIRESKANDARI , ASIM ALI","doi":"10.1016/j.ajo.2024.09.034","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose</h3><div>To describe the clinical and histopathologic features of pediatric eyelid cutaneous horns.</div></div><div><h3>Design</h3><div>Retrospective observational case series and review of literature.</div></div><div><h3>Subjects</h3><div>Five pediatric patients with eyelid cutaneous horns.</div></div><div><h3>Methods</h3><div>Five cases with eyelid cutaneous horns were retrospectively identified using departmental databases. Patients’ records were analyzed for demographic data, clinical appearance, histologic findings, and clinical course. An excisional biopsy of the lesion was performed in 3 patients. The remaining 2 patients were managed conservatively.</div></div><div><h3>Main outcome measures</h3><div>Clinical outcome and histopathologic evaluation with emphasis on excluding malignancy.</div></div><div><h3>Results</h3><div>All 5 cutaneous horn lesions resolved surgically or conservatively. The average age at presentation was 6.6 years (range 5-11 years). Clinically, 4 lesions were preceded by a hordeolum or chalazion and all excised lesions had benign features on histologic examination. Mitotic figures or atypia were not observed. None of the patients developed recurrence during the follow-up period ranging from 1 to 96 months.</div><div>Five previous reports of five cases were found on review of the literature. Our case series doubles this number to support the benign nature of these lesions in children.</div></div><div><h3>Conclusions</h3><div>Pediatric eyelid cutaneous horns are closely related to eyelid margin inflammatory disease and appear to follow a benign course. This contrasts with the adult population where cutaneous horns are frequently associated with neoplasia.</div></div>","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"269 ","pages":"Pages 482-487"},"PeriodicalIF":4.1000,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Ophthalmology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0002939424004653","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose
To describe the clinical and histopathologic features of pediatric eyelid cutaneous horns.
Design
Retrospective observational case series and review of literature.
Subjects
Five pediatric patients with eyelid cutaneous horns.
Methods
Five cases with eyelid cutaneous horns were retrospectively identified using departmental databases. Patients’ records were analyzed for demographic data, clinical appearance, histologic findings, and clinical course. An excisional biopsy of the lesion was performed in 3 patients. The remaining 2 patients were managed conservatively.
Main outcome measures
Clinical outcome and histopathologic evaluation with emphasis on excluding malignancy.
Results
All 5 cutaneous horn lesions resolved surgically or conservatively. The average age at presentation was 6.6 years (range 5-11 years). Clinically, 4 lesions were preceded by a hordeolum or chalazion and all excised lesions had benign features on histologic examination. Mitotic figures or atypia were not observed. None of the patients developed recurrence during the follow-up period ranging from 1 to 96 months.
Five previous reports of five cases were found on review of the literature. Our case series doubles this number to support the benign nature of these lesions in children.
Conclusions
Pediatric eyelid cutaneous horns are closely related to eyelid margin inflammatory disease and appear to follow a benign course. This contrasts with the adult population where cutaneous horns are frequently associated with neoplasia.
期刊介绍:
The American Journal of Ophthalmology is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and visual science specialists describing clinical investigations, clinical observations, and clinically relevant laboratory investigations. Published monthly since 1884, the full text of the American Journal of Ophthalmology and supplementary material are also presented online at www.AJO.com and on ScienceDirect.
The American Journal of Ophthalmology publishes Full-Length Articles, Perspectives, Editorials, Correspondences, Books Reports and Announcements. Brief Reports and Case Reports are no longer published. We recommend submitting Brief Reports and Case Reports to our companion publication, the American Journal of Ophthalmology Case Reports.
Manuscripts are accepted with the understanding that they have not been and will not be published elsewhere substantially in any format, and that there are no ethical problems with the content or data collection. Authors may be requested to produce the data upon which the manuscript is based and to answer expeditiously any questions about the manuscript or its authors.