Neuromodulation in Spinal Cord Injury Using Transcutaneous Spinal Stimulation-Mapping for a Blood Pressure Response: A Case Series.

IF 1.8 Q3 CLINICAL NEUROLOGY
Neurotrauma reports Pub Date : 2024-09-20 eCollection Date: 2024-01-01 DOI:10.1089/neur.2024.0066
Einat Engel-Haber, Akhil Bheemreddy, Mehmed Bugrahan Bayram, Manikandan Ravi, Fan Zhang, Haiyan Su, Steven Kirshblum, Gail F Forrest
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引用次数: 0

Abstract

Spinal cord transcutaneous stimulation (scTS) offers a promising approach to enhance cardiovascular regulation in individuals with a high-level spinal cord injury (SCI), addressing the challenges of unstable blood pressure (BP) and the accompanying hypo- and hypertensive events. While scTS offers flexibility in stimulation locations, it also leads to significant variability and lack of validation in stimulation sites utilized by studies. Our study presents findings from a case series involving eight individuals with chronic cervical SCI, examining the hemodynamic effects of scTS applied in different vertebral locations, spanning from high cervical to sacral regions. Stimulation of the lumbosacral vertebrae region (L1/2, S1/2, and also including T11/12) significantly elevated BP, unlike cervical or upper thoracic stimulation. The observed trend, which remained consistent across different participants, highlights the promising role of lumbosacral stimulation in neuromodulating BP.

经皮脊髓刺激脊髓损伤的神经调节--映射血压反应:病例系列。
脊髓经皮刺激(scTS)是一种很有前景的方法,它能增强脊髓高度损伤(SCI)患者的心血管调节能力,解决血压(BP)不稳定以及随之而来的低血压和高血压问题。虽然 scTS 在刺激位置上具有灵活性,但它也导致研究中使用的刺激位置存在很大的差异,而且缺乏验证。我们的研究介绍了一个涉及八名慢性颈椎 SCI 患者的病例系列,研究了从高颈椎到骶椎等不同椎体位置应用 scTS 对血液动力学的影响。与颈椎或上胸椎刺激不同,腰骶椎区(L1/2、S1/2,也包括 T11/12)的刺激可显著升高血压。观察到的趋势在不同的参与者中保持一致,这凸显了腰骶部刺激在神经调节血压方面的重要作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.40
自引率
0.00%
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审稿时长
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