Retinoid-enhanced human gastruloids

IF 17.3 1区生物学 Q1 CELL BIOLOGY

Nature Cell Biology Pub Date : 2024-10-10 DOI:10.1038/s41556-024-01517-5

Alexandra Schauer, Jesse V. Veenvliet

引用次数: 0

Abstract

Hidden by the womb, early human development remains cloaked in mystery. To unveil developmental processes in health and disease, pluripotent stem cells can be coaxed into structures recapitulating aspects of the embryo. A study now establishes an advanced stem-cell-based model of the human embryonic trunk.

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维甲酸增强型人类胃泌素

人类的早期发育被子宫所掩盖，至今仍是个谜。为了揭示健康和疾病的发育过程，可以将多能干细胞诱导成重现胚胎各方面的结构。现在，一项研究建立了基于干细胞的人类胚胎躯干先进模型。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Cell Biology 生物-细胞生物学

CiteScore

28.40

自引率

0.90%

发文量

219

审稿时长

3 months

期刊介绍： Nature Cell Biology, a prestigious journal, upholds a commitment to publishing papers of the highest quality across all areas of cell biology, with a particular focus on elucidating mechanisms underlying fundamental cell biological processes. The journal's broad scope encompasses various areas of interest, including but not limited to: -Autophagy -Cancer biology -Cell adhesion and migration -Cell cycle and growth -Cell death -Chromatin and epigenetics -Cytoskeletal dynamics -Developmental biology -DNA replication and repair -Mechanisms of human disease -Mechanobiology -Membrane traffic and dynamics -Metabolism -Nuclear organization and dynamics -Organelle biology -Proteolysis and quality control -RNA biology -Signal transduction -Stem cell biology