Twenty-Seven-Year Institutional Experience With Surgery for Adults With Congenital Heart Disease.

Aeleia F Hughes, Jeremy L Herrmann, Mark D Rodefeld, James E Slaven, Mark W Turrentine, John W Brown
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Abstract

Background: Given improved contemporary survival of adults with congenital heart disease (ACHD), we aimed to evaluate trends in ACHD surgery and outcomes at a single center over a 27-year period.

Methods: Surgical databases were retrospectively queried for patients >18 years old who underwent ACHD surgery between January 1, 1994, and December 31, 2020. A total of 2,195 included patients underwent 2,425 cardiac surgical procedures within the specified time frame. Patients were grouped by era: I, 1994-2000; 2, 2001-2010; and 3, 2011-2020. Trends in primary cardiac diagnosis and surgical management were evaluated.

Results: The median age increased across the eras. The most common primary cardiac diagnoses (n = 2,425) overall were left ventricular outflow tract anomalies (n = 2,019, 83%), atrial septal defect (n = 407, 17%), right ventricular outflow tract anomalies (n = 360, 15%), and ventricular septal defect (n = 110, 4.5%). The most commonly observed procedures overall were operations on the left ventricular outflow tract (n = 1,633, 67%), aorta (n = 675, 28%), coronary arteries (n = 449, 19%), right ventricular outflow tract (n = 323, 13%), and atrial septal defect (n = 264, 11%). Major complications occurred in 10% of cases, and 58 patients died within 30 days of their operation yielding an operative mortality of 2.4%.

Conclusion: To our knowledge, this is the largest single center report on surgery for adults with congenital heart disease. Surgery for ACHD has been performed at our center with relatively low morbidity and mortality over the last few decades.

成人先天性心脏病手术治疗二十七年的机构经验。
背景:鉴于当代成人先天性心脏病(ACHD)患者的生存率有所提高,我们旨在评估一个中心在 27 年间 ACHD 手术的趋势和结果:我们对 1994 年 1 月 1 日至 2020 年 12 月 31 日期间接受 ACHD 手术的 18 岁以上患者的手术数据库进行了回顾性查询。共有 2195 名患者在规定时间内接受了 2425 例心脏外科手术。患者按年代分组:I,1994-2000 年;2,2001-2010 年;3,2011-2020 年。评估了心脏初诊和手术治疗的趋势:结果:各年代的中位年龄均有所上升。最常见的原发性心脏病诊断(n = 2,425)为左室流出道异常(n = 2,019,83%)、房间隔缺损(n = 407,17%)、右室流出道异常(n = 360,15%)和室间隔缺损(n = 110,4.5%)。最常见的手术包括左室流出道(1633 例,67%)、主动脉(675 例,28%)、冠状动脉(449 例,19%)、右室流出道(323 例,13%)和房间隔缺损(264 例,11%)。10%的病例出现了重大并发症,58名患者在手术后30天内死亡,手术死亡率为2.4%:据我们所知,这是关于成人先天性心脏病手术的最大规模的单中心报告。结论:据我们所知,这是关于成人先天性心脏病手术的最大规模的单个中心报告。在过去的几十年里,我们中心开展的先天性心脏病手术的发病率和死亡率都相对较低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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