Energy-integrating detector based ultra-high-resolution CT with deep learning reconstruction for the assessment of calcified lesions in coronary artery disease

IF 5.5 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
Misato Sone , Makoto Orii , Yoshitaka Ota , Takuya Chiba , Joanne D. Schuijf , Naruomi Akino , Kunihiro Yoshioka
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引用次数: 0

Abstract

Background

The aim of this study to compare of the image quality of calcified lesions in coronary artery disease between deep learning reconstruction (DLR) and model-based iterative reconstruction (MBIR) on energy-integrating detector (EID) based ultra-high-resolution CT (UHRCT).

Methods

We performed a phantom study on EID-based UHRCT using a dedicated insert for calcifications and obtained the derivative values for DLR and MBIR. In the clinical study, the derivative values were compared between DLR and MBIR across 73 calcified lesions in 62 patients. Edge sharpness of calcifications and contrast resolution at the coronary lumen side were quantified by the maximum and minimum derivative values. Two radiologists independently analyzed image quality of the calcified lesions using a 5-point Likert scale.

Results

In the phantom study, the edge sharpness of the 3-mm calcifications on DLR (median, 924 HU/mm; IQR, 580–1741 HU/mm) was significantly higher than on MBIR (median, 835 HU/mm; IQR, 484–1552; p ​< ​0.001). In the clinical study, the image quality of the calcified lesions was significantly better on DLR with significantly reduced reconstruction time (p ​< ​0.001). The contrast resolution at the coronary lumen side on DLR (median, −99.1 HU/mm; IQR, −209 to −34.3 HU/mm) was significantly higher than on MBIR (median, −41.8 HU/mm; IQR, −121 to 22.3 HU/mm, p ​< ​0.001) although the edge sharpness of calcifications was similar between DLR and MBIR (p ​= ​0.794) in the clinical setting.

Conclusion

EID-based UHRCT reconstructed using DLR represents better image quality of calcified lesions in coronary artery disease compared with MBIR, with significantly reduced reconstruction time.
基于能量积分探测器的超高分辨率 CT 与深度学习重建用于评估冠状动脉疾病的钙化病变。
研究背景本研究旨在比较基于能量积分探测器(EID)的超高分辨率 CT(UHRCT)上深度学习重建(DLR)和基于模型的迭代重建(MBIR)对冠状动脉疾病钙化病变的成像质量:我们使用钙化专用插入物对基于 EID 的 UHRCT 进行了模型研究,并获得了 DLR 和 MBIR 的导数值。在临床研究中,我们对 62 名患者的 73 个钙化病灶的 DLR 和 MBIR 的导数值进行了比较。钙化的边缘锐利度和冠状动脉管腔侧的对比分辨率通过最大和最小导数值进行量化。两名放射科医生使用 5 点李克特量表独立分析了钙化病变的图像质量:结果:在模型研究中,DLR(中位数,924 HU/mm;IQR,580-1741 HU/mm)上 3 毫米钙化的边缘锐利度明显高于 MBIR(中位数,835 HU/mm;IQR,484-1552;P 结论:与 MBIR 相比,使用 DLR 重建的基于 EID 的 UHRCT 对冠状动脉疾病钙化病变的成像质量更好,重建时间也明显缩短。
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来源期刊
Journal of Cardiovascular Computed Tomography
Journal of Cardiovascular Computed Tomography CARDIAC & CARDIOVASCULAR SYSTEMS-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
CiteScore
7.50
自引率
14.80%
发文量
212
审稿时长
40 days
期刊介绍: The Journal of Cardiovascular Computed Tomography is a unique peer-review journal that integrates the entire international cardiovascular CT community including cardiologist and radiologists, from basic to clinical academic researchers, to private practitioners, engineers, allied professionals, industry, and trainees, all of whom are vital and interdependent members of our cardiovascular imaging community across the world. The goal of the journal is to advance the field of cardiovascular CT as the leading cardiovascular CT journal, attracting seminal work in the field with rapid and timely dissemination in electronic and print media.
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