Influence of vitamin D on muscle strength and botulinum toxin dosage through surface electromyography.

Acta cirurgica brasileira Pub Date : 2024-10-07 eCollection Date: 2024-01-01 DOI:10.1590/acb396824

Marcelle Simões Coelho, Gabriel Cirone Lopes, Luigi Giovanni Bernardo Sichi, Sigmar de Mello Rode, Rodrigo Máximo de Araújo

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Abstract

Purpose: To evaluate the influence of patients' serum vitamin D levels on muscle strength characteristics and whether it impacts the durability of botulinum toxin (BT) treatment.

Methods: The muscle strength of the frontal and corrugator muscles was evaluated before and after the application of TB with pre- and post-application control measurements, and at weeks 2, 5 and 12. The effect of vitamin D on muscle strength and its interaction with BT were investigated in 20 patients. The muscle contraction force was measured by surface electromyography.

Results: The results revealed statistically significant differences between the frontal measurement groups at weeks 2 and 5, as well as for the corrugator in the same weeks and at week 12. Regarding vitamin D, significant differences were observed only in the initial group with vitamin D > 30 ng/mL compared to < 30 ng/mL for the frontal muscles. Patients with higher levels of vitamin D had higher average muscle strength compared to those with lower levels in all evaluations.

Conclusions: It was observed that vitamin D influences muscle strength and the necessary dosage of BT.

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通过表面肌电图观察维生素 D 对肌肉力量和肉毒杆菌毒素剂量的影响。

目的：评估患者血清维生素 D 水平对肌肉力量特征的影响，以及是否会影响肉毒杆菌毒素（BT）治疗的持久性：方法：在使用肉毒杆菌毒素前后进行对照测量，并在第 2、5 和 12 周时评估额肌和皱纹肌的肌力。在 20 名患者中调查了维生素 D 对肌肉力量的影响及其与 BT 的相互作用。通过表面肌电图测量肌肉收缩力：结果表明，在第 2 周和第 5 周，额肌测量组之间存在统计学意义上的显著差异；在第 2 周和第 5 周以及第 12 周，耸肌测量组之间也存在统计学意义上的显著差异。在维生素 D 方面，只有维生素 D > 30 纳克/毫升的初始组与维生素 D < 30 纳克/毫升的额肌组之间存在显著差异。在所有评估中，维生素 D 水平较高的患者的平均肌肉力量高于维生素 D 水平较低的患者：观察发现，维生素 D 会影响肌肉力量和 BT 的必要剂量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Acta cirurgica brasileira

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