Elizabeth T Mendoza, María Villada, Maria Carolina Velásquez-Martínez
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引用次数: 0
Abstract
Ethanol consumption is among the first five substances with higher risk associated with diseases, disability, and death in the world. Anxiety behavior has been linked to ethanol-addictive conduct. The aim of the present study was to evaluate three strains with differential anxiety behavior: a Wild-type strain; a "Reactive" strain, with an increase in anxiety-related behaviors; and a "Non-Reactive" strain, with lower anxiety-related behaviors, before and after the voluntary consumption of ethanol (10%) protocol. To evaluate anxiety, animals were exposed to the elevated plus-maze 24 h before and after the consumption protocol. On the voluntary consumption of ethanol protocol, the animals were exposed to a water and an ethanol bottle. The weight of the liquid consumed daily for 40 days was registered. Results: all strains increased ethanol vs water consumption: Wild-type: day 8; R: day 10; NR: day 31. Ethanol consumption reduced the number and percentage of open arms entries only on the Wild-type strain. Conclusion: anxiety can predispose to an increase in ethanol consumption and to the maintenance of anxiety-related behaviors.
期刊介绍：
The International Journal of Psychological Research (Int.j.psychol.res) is the Faculty of Psychology’s official publication of San Buenaventura University in Medellin, Colombia. Int.j.psychol.res relies on a vast and diverse theoretical and thematic publishing material, which includes unpublished productions of diverse psychological issues and behavioral human areas such as psychiatry, neurosciences, mental health, among others.
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