The Swedish sleep apnea registry (SESAR) cohort – “Real world data” on a national level

IF 3.8 2区医学 Q1 CLINICAL NEUROLOGY

Sleep medicine Pub Date : 2024-09-29 DOI:10.1016/j.sleep.2024.09.039

Ludger Grote , Yvonne Asp Jonzon , Peter Barta , Tarmo Murto , Zarita Nilsson , Anna Nygren , Jenny Theorell-Haglöw , Ola Sunnergren , Martin Ulander , Magnus Ekström , Andreas Palm , Jan Hedner

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引用次数: 0

Abstract

Introduction

The Swedish Sleep Apnea Registry (SESAR) collects clinical data from individual obstructive sleep apnea (OSA) patients since 2010. SESAR has recently been integrated with additional national healthcare data. The current analysis presents the SESAR structure and representative clinical data of a national sleep apnea cohort.

Methods

Clinical data from unselected patients with a diagnosis of OSA are submitted to the SESAR registry. 48 sleep centers report data from diagnosis, treatment starts with Continuous Positive Airway Pressure (CPAP), oral devices (OD), and Upper Airway Surgery (UAS). Data from follow-up are included. SESAR is linked to mandatory national healthcare data (mortality, comorbidities, procedures, prescriptions) and diagnosis-specific quality registries (e.g. stroke, heart failure, diabetes) within the DISCOVERY project.

Results

83,404 OSA patients have been reported during the diagnostic workup (age 55.4 ± 14.1 years, BMI 30.8 ± 6.5 kg/m², AHI 25.8 ± 21.6n/h, respectively). At least one cardiometabolic and respiratory comorbidity is recognized in 57 % of female and 53 % of male OSA patients with a linear increase across OSA severity. In 54,468, 7,797, and 390 patients, start of CPAP, OD or UAS treatment is reported, respectively. OD patients have 4 units lower BMI and 10 units lower AHI compared to patients started on CPAP. UAS patients are characterized by 10 years lower age. The degree of daytime sleepiness is comparable between treatment groups with mean Epworth Sleepiness Scale Scores between 9 and 10.

Conclusion

SESAR is introduced as a large national registry of OSA patients. SESAR provides a useful tool to highlight OSA management and to perform relevant outcome research.

查看原文本刊更多论文

瑞典睡眠呼吸暂停登记（SESAR）队列--全国范围内的 "真实数据"。

简介：瑞典睡眠呼吸暂停登记处（SESAR）自 2010 年起开始收集阻塞性睡眠呼吸暂停（OSA）患者的临床数据。最近，SESAR 与其他国家医疗保健数据进行了整合。本次分析介绍了 SESAR 的结构和全国睡眠呼吸暂停队列的代表性临床数据：方法：未经筛选的 OSA 诊断患者的临床数据提交给 SESAR 登记处。48 家睡眠中心报告了诊断数据、开始使用持续气道正压（CPAP）、口腔装置（OD）和上气道手术（UAS）的治疗数据。随访数据也包括在内。SESAR 与 DISCOVERY 项目中的强制性国家医疗保健数据（死亡率、合并症、手术、处方）和特定诊断质量登记（如中风、心力衰竭、糖尿病）相关联：在诊断过程中，共报告了 83 404 名 OSA 患者（年龄分别为 55.4 ± 14.1 岁、体重指数为 30.8 ± 6.5 kg/m2、AHI 为 25.8 ± 21.6n/h）。57%的女性 OSA 患者和 53% 的男性 OSA 患者至少患有一种心脏代谢和呼吸系统并发症，且 OSA 严重程度呈线性增长。据报告，分别有 54,468 名、7,797 名和 390 名患者开始接受 CPAP、OD 或 UAS 治疗。与开始使用 CPAP 的患者相比，OD 患者的 BMI 降低了 4 个单位，AHI 降低了 10 个单位。UAS 患者的特点是年龄小 10 岁。各治疗组的白天嗜睡程度相当，平均埃普沃思嗜睡量表评分在 9 分至 10 分之间：SESAR 是一个大型的全国性 OSA 患者登记系统。结论：SESAR 是一项大型的全国性 OSA 患者登记项目，为突出 OSA 的管理和开展相关结果研究提供了有用的工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Sleep medicine 医学-临床神经学

CiteScore

8.40

自引率

6.20%

发文量

1060

审稿时长

49 days

期刊介绍： Sleep Medicine aims to be a journal no one involved in clinical sleep medicine can do without. A journal primarily focussing on the human aspects of sleep, integrating the various disciplines that are involved in sleep medicine: neurology, clinical neurophysiology, internal medicine (particularly pulmonology and cardiology), psychology, psychiatry, sleep technology, pediatrics, neurosurgery, otorhinolaryngology, and dentistry. The journal publishes the following types of articles: Reviews (also intended as a way to bridge the gap between basic sleep research and clinical relevance); Original Research Articles; Full-length articles; Brief communications; Controversies; Case reports; Letters to the Editor; Journal search and commentaries; Book reviews; Meeting announcements; Listing of relevant organisations plus web sites.