Rare presentation of primary synovial chondrosarcoma arising in the shoulder: a case report.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Kengo Kawaguchi, Makoto Endo, Koji Sagiyama, Akira Maekawa, Akira Nabeshima, Toshifumi Fujiwara, Yoshinao Oda, Yasuharu Nakashima
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Abstract

Synovial chondrosarcoma (CHS) is a rare malignant tumor arising from the synovial tissue and is often associated with synovial chondromatosis. Herein, we present a unique case of primary synovial CHS in the shoulder joint without evidence of synovial chondromatosis. A 60-year-old man presented to our hospital with a complain of left shoulder pain that persisted for 6 years, which was initially misdiagnosed as synovitis. Radiography revealed an osteolytic lesion involving the humerus and the scapula. Histologically, the tumor exhibited features of grade 2 synovial CHS, infiltrating the trabecular bones and intra-articular space. Wide resection led to a 9-year recurrence-free survival. This case underscores the challenges in diagnosing and managing synovial CHS, particularly in cases with atypical presentations lacking synovial chondromatosis, necessitating careful follow-up and adequate surgical intervention.

肩部原发性滑膜软骨肉瘤的罕见表现:病例报告。
滑膜软骨肉瘤(CHS)是一种罕见的发生于滑膜组织的恶性肿瘤,通常与滑膜软骨瘤病相关。在此,我们将介绍一例独特的肩关节原发性滑膜 CHS 病例,该病例无滑膜软骨瘤病的证据。一名 60 岁的男性因左肩疼痛就诊于我院,疼痛持续了 6 年,最初被误诊为滑膜炎。影像学检查发现肱骨和肩胛骨有溶骨性病变。从组织学角度看,肿瘤表现出2级滑膜CHS的特征,浸润骨小梁和关节内间隙。广泛切除后,患者获得了9年无复发生存。该病例强调了诊断和治疗滑膜CHS的挑战,尤其是在缺乏滑膜软骨瘤病的非典型病例中,需要仔细随访和适当的手术干预。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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