Patient-Reported Outcomes in Metabolic Dysfunction-Associated Steatotic Liver Disease.

IF 4.3 3区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY
Aurora Barberá, Trenton M White, Anish K Arora, Linda Henry, Jeffrey V Lazarus, Zobair M Younossi
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引用次数: 0

Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide and can progress to serious complications, including metabolic dysfunction-associated steatohepatitis (MASH), cirrhosis, end-stage liver disease, and hepatocellular carcinoma. Predisposing risk factors for MASH include obesity, type 2 diabetes, dyslipidemia, and metabolic syndrome. Patients with MASH often experience significant impairments in their health-related quality of life and other patient-reported outcomes (PROs), particularly in physical functioning domains, fatigue, and vitality. Incorporating PROs offers valuable insights into patients' perspectives on their symptoms, treatment efficacy, and overall well-being, thereby guiding more holistic and patient-centered care strategies. This review aims to investigate the utilization of patient-reported outcome measures (PROMs) in the context of MASLD and MASH care, identify which PROMs are employed, and summarize the outcomes reported.

代谢功能障碍相关性脂肪肝的患者报告结果
代谢功能障碍相关性脂肪性肝病(MASLD)是全球最常见的慢性肝病,可发展为严重的并发症,包括代谢功能障碍相关性脂肪性肝炎(MASH)、肝硬化、终末期肝病和肝细胞癌。易导致 MASH 的风险因素包括肥胖、2 型糖尿病、血脂异常和代谢综合征。MASH患者的健康相关生活质量(HRQoL)和其他患者报告结果(PROs)通常会受到严重影响,尤其是在身体功能领域。纳入PROs可以让人们深入了解患者对其症状、治疗效果和整体健康的看法,从而指导更加全面和以患者为中心的护理策略。本综述旨在调查 MASLD 和 MASH 护理中患者报告结果测量(PROMs)的使用情况,确定采用了哪些 PROMs,并总结报告的结果。
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来源期刊
Seminars in liver disease
Seminars in liver disease 医学-胃肠肝病学
CiteScore
8.20
自引率
2.40%
发文量
38
期刊介绍: Seminars in Liver Disease is a quarterly review journal that publishes issues related to the specialties of hepatology and gastroenterology. As the premiere review journal in the field, Seminars in Liver Disease provides in-depth coverage with articles and issues focusing on topics such as cirrhosis, transplantation, vascular and coagulation disorders, cytokines, hepatitis B & C, Nonalcoholic Steatosis Syndromes (NASH), pediatric liver diseases, hepatic stem cells, porphyrias as well as a myriad of other diseases related to the liver. Attention is also given to the latest developments in drug therapy along with treatment and current management techniques. Seminars in Liver Disease publishes commissioned reviews. Unsolicited reviews of an exceptional nature or original articles presenting remarkable results will be considered, but case reports will not be published.
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