Can Physical Therapy Techniques Slow Down the Progression of Lipedema?

IF 1.9 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Lymphatic research and biology Pub Date : 2024-12-01 Epub Date: 2024-10-09 DOI:10.1089/lrb.2024.0065
Murat Esmer, Franz Josef Schingale
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引用次数: 0

Abstract

Background: Lipedema is a disease characterized by an increase in extracellular fluid. In these patients, the increase in the amount of extracellular fluid may accelerate the progression of the disease. The aim of this study is to examine the effect of complex decongestive therapy (CDT) on intracellular/extracellular fluid balance. Methods and Results: Twenty-two female patients diagnosed with lipedema by a specialist lymphologist were included in the study. Patients were subjected to complex decongestive therapy and pneumatic compression therapy 6 days a week for 1 month. Extracellular and intracellular fluid volumes were assessed using bioimpedance spectroscopy before and after the treatment. A decrease in intracellular (p = 0.010) and extracellular (p = 0.002) fluid volumes was observed after the treatment. Conclusion: There is no completely curative treatment method for lipedema. Current treatments aim to slow down the progression of the disease. CDT is considered effective in reducing intracellular and extracellular fluid volume in lipedema patients. Therefore, it is thought to be effective in slowing down the progression of the disease.

物理治疗技术能延缓脂肪性水肿的发展吗?
背景:脂肪性水肿是一种以细胞外液增加为特征的疾病。在这些患者中,细胞外液的增加可能会加速疾病的进展。本研究旨在探讨复合去充血疗法(CDT)对细胞内/细胞外液体平衡的影响。方法和结果:22名女性患者被淋巴专科医生诊断为脂肪性水肿。患者接受了每周 6 天的复合减充血疗法和气压疗法,为期 1 个月。在治疗前后,使用生物阻抗光谱评估了细胞外和细胞内的液体量。治疗后观察到细胞内(p = 0.010)和细胞外(p = 0.002)液体量减少。结论目前还没有完全治愈脂肪性水肿的方法。目前的治疗方法旨在延缓疾病的进展。CDT 被认为能有效减少脂肪性水肿患者的细胞内和细胞外液容量。因此,它被认为能有效延缓疾病的进展。
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来源期刊
Lymphatic research and biology
Lymphatic research and biology Medicine-Cardiology and Cardiovascular Medicine
CiteScore
3.10
自引率
7.10%
发文量
85
审稿时长
>12 weeks
期刊介绍: Lymphatic Research and Biology delivers the most current peer-reviewed advances and developments in lymphatic biology and pathology from the world’s leading biomedical investigators. The Journal provides original research from a broad range of investigative disciplines, including genetics, biochemistry and biophysics, cellular and molecular biology, physiology and pharmacology, anatomy, developmental biology, and pathology. Lymphatic Research and Biology coverage includes: -Vasculogenesis and angiogenesis -Genetics of lymphatic disorders -Human lymphatic disease, including lymphatic insufficiency and associated vascular anomalies -Physiology of intestinal fluid and protein balance -Immunosurveillance and immune cell trafficking -Tumor biology and metastasis -Pharmacology -Lymphatic imaging -Endothelial and smooth muscle cell biology -Inflammation, infection, and autoimmune disease
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