Addition of Bioactive Glass Decreases Setting Time and Improves Antibacterial Properties of Mineral Trioxide Aggregate.

IF 3 Q3 MATERIALS SCIENCE, BIOMATERIALS

International Journal of Biomaterials Pub Date : 2024-07-23 eCollection Date: 2024-01-01 DOI:10.1155/2024/4190647

Amin Salem Milani, Faezeh Hadinia, Yashar Rezaei, Mohammad Hossein Soroush Barhaghi, Kamal Attari, Ahmad Nouroloyouni

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引用次数: 0

Abstract

Objectives: This study aimed to assess the effect of addition of bioactive glass (BG) on the setting time and antibacterial activity of mineral trioxide aggregate (MTA) against Enterococcus faecalis (E. faecalis).

Materials and methods: In this in vitro study, BG was synthesized by the sol-gel technique and added to MTA powder in certain ratios. Three groups of specimens were fabricated from pure MTA, MTA mixed with 10wt% BG, and MTA mixed with 20wt% BG. The setting time of specimens was measured according to ISO9917-2007. Direct contact test was used to assess the antimicrobial activity of the three groups against E. faecalis. Data were analyzed by repeated measures ANOVA (alpha = 0.05).

Results: Addition of BG (in both concentrations) to MTA decreased its setting time and improved its antibacterial activity against E. faecalis (p < 0.05). By an increase in concentration of BG (20%), the antimicrobial activity further improved (p < 0.05).

Conclusion: Addition of BG to MTA in 10wt% and 20wt% concentrations decreased its setting time and improved its antibacterial activity against E. faecalis.

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添加生物活性玻璃可缩短三氧化二铝矿物骨料的凝结时间并改善其抗菌性能。

研究目的本研究旨在评估添加生物活性玻璃（BG）对三氧化物矿物质骨料（MTA）的凝结时间和粪肠球菌（E. faecalis）抗菌活性的影响：在这项体外研究中，采用溶胶-凝胶技术合成了 BG，并按一定比例添加到 MTA 粉末中。由纯 MTA、混合了 10wt% BG 的 MTA 和混合了 20wt% BG 的 MTA 制成了三组试样。根据 ISO9917-2007 测量了试样的凝固时间。直接接触试验用于评估三组材料对粪大肠杆菌的抗菌活性。数据采用重复测量方差分析（α = 0.05）：结果：在 MTA 中添加 BG（两种浓度）可缩短其凝固时间并提高其对粪肠球菌的抗菌活性（p < 0.05）。随着 BG 浓度的增加（20%），抗菌活性进一步提高（p < 0.05）：结论：在浓度为 10wt% 和 20wt% 的 MTA 中添加 BG 缩短了凝固时间，并提高了其对粪肠球菌的抗菌活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Biomaterials MATERIALS SCIENCE, BIOMATERIALS-

CiteScore

4.30

自引率

3.20%

发文量

审稿时长

21 weeks