The conundrum of CD8+ T cell trajectories in low antigenic tumors: How to overcome a hypofunctional state distinct from antigen-driven exhaustion?

IF 5 3区医学 Q1 GENETICS & HEREDITY

Genes and immunity Pub Date : 2024-10-09 DOI:10.1038/s41435-024-00299-y

Angeliki Datsi, Rüdiger V. Sorg, Abhishek D. Garg

引用次数: 0

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低抗原肿瘤中 CD8+ T 细胞轨迹的难题：如何克服不同于抗原驱动衰竭的低功能状态？

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来源期刊

Genes and immunity 医学-免疫学

CiteScore

8.90

自引率

4.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Genes & Immunity emphasizes studies investigating how genetic, genomic and functional variations affect immune cells and the immune system, and associated processes in the regulation of health and disease. It further highlights articles on the transcriptional and posttranslational control of gene products involved in signaling pathways regulating immune cells, and protective and destructive immune responses.