No evidence of improvements in energy metabolism after 1 week of nitrate and citrulline co-supplementation in elite rowers.

IF 2.8 3区医学 Q2 PHYSIOLOGY

European Journal of Applied Physiology Pub Date : 2025-03-01 Epub Date: 2024-10-09 DOI:10.1007/s00421-024-05636-7

Aitor Viribay, Juan M A Alcantara, Iker López, Juan Mielgo-Ayuso, Arkaitz Castañeda-Babarro

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引用次数: 0

Abstract

Purpose: Citrulline (CIT) and beetroot extract (BR) supplements positively impacts exercise performance in elite rowers. However, its influence on metabolic outcomes such as whole-body volumes of oxygen consumption (VO₂) and carbon dioxide production (VCO₂), substrate oxidation, energy expenditure (EE), and gross efficiency remains unknown. We studied the effects of 1 week of daily co-supplementation of 3.5 g BR (500 mg NO₃^-) plus 6 g CIT on VO₂ and VCO₂ kinetics, substrate utilization, EE, and gross efficiency in elite male rowers compared to a placebo and to a BR supplementation.

Methods: Twenty elite rowers participated in this randomized, double-blind, placebo-controlled crossover trial completing 1 week of supplementation in each group of study: Placebo (PLAG); BRG; and BR-CITG. Efficiency (70% VO_2max) and performance (incremental maximal) tests were performed, and gas-exchange data were collected via indirect calorimetry.

Results: Analysis of covariance (ANCOVA) showed no mean between-condition differences on respiratory exchange ratio (RER), EE, and gross efficiency in the efficiency test (all P > 0.06), and in the performance test (all P > 0.28). Moreover, in both tests no interaction Time × Supplement effects were observed for VO₂, VCO₂, RER, EE, substrate oxidation, and, gross efficiency (all P > 0.12).

Conclusion: After 1 week, no effects on energy metabolism and substrate utilization were observed after the daily co-ingestion of BR extract plus CIT supplement, therefore longer (> 7 days) and higher doses of supplementation might be needed to influence metabolism.

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在精英赛艇运动员中同时补充硝酸盐和瓜氨酸一周后，没有证据表明能量代谢有所改善。

目的：瓜氨酸（CIT）和甜菜根提取物（BR）补充剂对精英赛艇运动员的运动表现有积极影响。然而，其对全身耗氧量（VO2）和二氧化碳产生量（VCO2）、底物氧化、能量消耗（EE）和总效率等代谢结果的影响仍然未知。我们研究了每天补充 3.5 克 BR（500 毫克 NO3-）和 6 克 CIT，与安慰剂和 BR 补充剂相比，对精英男子赛艇运动员的 VO2 和 VCO2 动力学、底物利用、EE 和总效率的影响：20 名精英赛艇运动员参加了这项随机、双盲、安慰剂对照交叉试验，每组研究均完成 1 周的补充：安慰剂 (PLAG)、BRG 和 BR-CITG。进行了效率（70% VO2max）和性能（最大增量）测试，并通过间接热量计收集了气体交换数据：协方差分析（ANCOVA）显示，在效率测试（所有 P > 0.06）和成绩测试（所有 P > 0.28）中，呼吸交换比（RER）、EE 和总效率没有条件间平均差异。此外，在这两项测试中，VO2、VCO2、RER、EE、底物氧化和总效率均未观察到时间 × 补充剂的交互影响（所有 P > 0.12）：一周后，每天同时摄入 BR 提取物和 CIT 补充剂对能量代谢和底物利用没有影响，因此可能需要更长时间（> 7 天）和更大剂量的补充剂来影响代谢。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Applied Physiology 医学-生理学

CiteScore

6.00

自引率

6.70%

发文量

227

审稿时长

3 months

期刊介绍： The European Journal of Applied Physiology (EJAP) aims to promote mechanistic advances in human integrative and translational physiology. Physiology is viewed broadly, having overlapping context with related disciplines such as biomechanics, biochemistry, endocrinology, ergonomics, immunology, motor control, and nutrition. EJAP welcomes studies dealing with physical exercise, training and performance. Studies addressing physiological mechanisms are preferred over descriptive studies. Papers dealing with animal models or pathophysiological conditions are not excluded from consideration, but must be clearly relevant to human physiology.