Effect of replacing Bis-GMA with a biobased trimethacrylate on the physicochemical and mechanical properties of experimental resin composites.

IF 3.1 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Oral Investigations Pub Date : 2024-10-08 DOI:10.1007/s00784-024-05959-x

Madiana Magalhães Moreira, Ana Larissa da Silva, Rita de Cássia Sousa Pereira, Lucas Renan Rocha da Silva, Victor Pinheiro Feitosa, Diego Lomonaco

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引用次数: 0

Abstract

Objectives: To analyze the incorporation of cardanol trimethacrylate monomer (CTMA), derived from the cashew nut shell liquid, as a substitute for Bis-GMA in acrylic resins formulations and its effect on experimental resin composites' physicochemical and mechanical properties.

Materials and methods: The intermediary cardanol epoxy was synthesized via cardanol epoxidation, followed by the synthesis of CTMA through methacrylic anhydride solvent-free esterification. Experimental resin composites were formulated with an organic matrix composed of Bis-GMA/TEGDMA (50/50 wt %) (control). CTMA was gradually added to replace different proportions of Bis-GMA: 10 wt % (CTMA-10), 20 wt % (CTMA-20), 40 wt % (CTMA-40), and 50 wt % (CTMA-50). The composites were characterized by degree of conversion, water sorption and solubility, viscosity, thermogravimetric analysis, dynamic mechanical analysis, flexural strength and elastic modulus. Data were analyzed with one-way ANOVA and Tukey's post-hoc test (α = 0.05), except for water sorption data, which were analyzed by Kruskall-Wallis and Dunn's method.

Results: CTMA-based and control composites did not show statistically significant differences regarding degree of conversion, flexural strength and elastic modulus. CTMA reduced the viscosity and solubility compared to the Bis-GMA-based composite. The CTMA-40 and CTMA-50 exhibited significantly lower water sorption compared to the control. Also, acceptable thermal stability and viscoelastic properties were obtained for safe use in the oral cavity.

Conclusions: Incorporating CTMA into composites resulted in similar chemical and mechanical properties compared to Bis-GMA-based material while reducing viscosity, water sorption and solubility.

Clinical relevance: CTMA could be used as a trimethacrylate monomer replacing Bis-GMA in resin composites, thereby minimizing BPA exposure.

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用生物基三甲基丙烯酸酯替代双-GMA 对实验性树脂复合材料的物理化学和机械性能的影响。

目的分析腰果壳液中提取的硬脂醇三甲基丙烯酸酯单体（CTMA）作为双甲基丙烯酸甲酯（Bis-GMA）的替代品加入丙烯酸树脂配方中的情况及其对实验树脂复合材料的物理化学和机械性能的影响：通过卡尔德酚环氧化反应合成中间体卡尔德酚环氧树脂，然后通过甲基丙烯酸酐无溶剂酯化反应合成 CTMA。实验用树脂复合材料由双-GMA/TEGDMA（50/50 wt %）（对照组）组成的有机基体配制。逐步添加 CTMA 以取代不同比例的 Bis-GMA：10 wt % (CTMA-10)、20 wt % (CTMA-20)、40 wt % (CTMA-40) 和 50 wt % (CTMA-50)。复合材料的特性包括转化率、吸水性和溶解性、粘度、热重分析、动态力学分析、抗弯强度和弹性模量。除吸水性数据采用 Kruskall-Wallis 和 Dunn 方法分析外，其他数据均采用单因素方差分析和 Tukey 后检验（α = 0.05）：结果：基于 CTMA 的复合材料与对照复合材料在转化率、抗弯强度和弹性模量方面的差异没有统计学意义。与基于 Bis-GMA 的复合材料相比，CTMA 降低了粘度和溶解度。与对照组相比，CTMA-40 和 CTMA-50 的吸水性明显降低。此外，CTMA 还具有可接受的热稳定性和粘弹性，可在口腔中安全使用：结论：在复合材料中加入 CTMA 可获得与基于双-GMA 的材料相似的化学和机械性能，同时降低粘度、吸水性和溶解性：临床意义：CTMA 可作为三甲基丙烯酸酯单体替代双-GMA 用于树脂复合材料中，从而最大限度地减少双酚 A 暴露。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Oral Investigations 医学-牙科与口腔外科

CiteScore

6.30

自引率

5.90%

发文量

484

审稿时长

3 months

期刊介绍： The journal Clinical Oral Investigations is a multidisciplinary, international forum for publication of research from all fields of oral medicine. The journal publishes original scientific articles and invited reviews which provide up-to-date results of basic and clinical studies in oral and maxillofacial science and medicine. The aim is to clarify the relevance of new results to modern practice, for an international readership. Coverage includes maxillofacial and oral surgery, prosthetics and restorative dentistry, operative dentistry, endodontics, periodontology, orthodontics, dental materials science, clinical trials, epidemiology, pedodontics, oral implant, preventive dentistiry, oral pathology, oral basic sciences and more.