Short-term outcome of endoscopic submucosal dissection using a clutch cutter for subepithelial lesions within the esophagogastric submucosa: a Japanese prospective observational study.

IF 2.1 Q3 GASTROENTEROLOGY & HEPATOLOGY
Kazuya Akahoshi, Kazuki Inamura, Kazuaki Akahoshi, Shigeki Osada, Shinichi Tamura, Yoshihiro Oishi, Masafumi Oya, Hidenobu Koga
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引用次数: 0

Abstract

Background/aims: The efficacy and safety of endoscopic submucosal dissection using a clutch cutter (ESD-CC) for subepithelial lesions within the esophagogastric submucosa (SELEGSM) has not been investigated. This study aimed to assess the efficacy and safety of ESD-CC for the treatment of SELEGSM.

Methods: This prospective study included 15 consecutive patients with 18 SELEGSMs diagnosed by endoscopic ultrasonography. The primary outcomes were short-term outcomes including en bloc resection rate, R0 resection rate, procedure time, and complication rate. The secondary outcome was final histological diagnosis.

Results: Among the participants, 18 lesions were identified: 12 in the stomach (nine patients) and six in the esophagus (six patients). The en bloc resection rate was 94.4% (17/18). The R0 resection rate was 88.9% (16/18). The median operating time was 39 min, and no instances of perforation or bleeding were observed. The final diagnoses of SELEGSM included six neuroendocrine tumors (33.3%), six granular cell tumors (33.3%), two ectopic pancreases (11.1%), one inflammatory fibroid polyp (5.6%), one leiomyoma (5.6%), one lipoma (5.6%), and one leiomyosarcoma (5.6%).

Conclusions: ESD-CC appears to be a technically efficient and safe approach for SELEGSM resection, suggesting its potential as a valuable treatment option.

使用离合器切割器对食管胃黏膜上皮下病变进行内镜黏膜下剥离术的短期疗效:一项日本前瞻性观察研究。
背景/目的:使用离合器切割器(ESD-CC)进行内镜黏膜下剥离术治疗食管胃黏膜上皮下病变(SELEGSM)的有效性和安全性尚未得到研究。本研究旨在评估ESD-CC治疗SELEGSM的有效性和安全性:这项前瞻性研究连续纳入了 15 例经内镜超声波检查确诊的 18 例 SELEGSM 患者。主要结果是短期结果,包括全切率、R0切除率、手术时间和并发症发生率。次要结果是最终的组织学诊断:结果:参与者中共发现 18 个病灶,其中 12 个位于胃部(9 名患者):结果:参与者中共发现 18 处病灶:胃部 12 处(9 名患者),食管 6 处(6 名患者)。整块切除率为 94.4%(17/18)。R0切除率为88.9%(16/18)。中位手术时间为 39 分钟,未观察到穿孔或出血情况。SELEGSM的最终诊断包括6个神经内分泌肿瘤(33.3%)、6个颗粒细胞瘤(33.3%)、2个异位胰腺(11.1%)、1个炎性纤维息肉(5.6%)、1个子宫肌瘤(5.6%)、1个脂肪瘤(5.6%)和1个子宫肌瘤(5.6%):ESD-CC似乎是一种技术上高效、安全的SELEGSM切除方法,表明它有可能成为一种有价值的治疗选择。
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来源期刊
Clinical Endoscopy
Clinical Endoscopy GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
4.40
自引率
8.00%
发文量
95
审稿时长
26 weeks
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