A simple method to remove polyimide coating from fused silica capillaries for capillary electrophoresis

IF 3.8 2区化学 Q1 BIOCHEMICAL RESEARCH METHODS

Journal of Chromatography A Pub Date : 2024-10-01 DOI:10.1016/j.chroma.2024.465395

引用次数: 0

Abstract

A simple and cost-effective method for making capillary electrophoresis (CE) detection windows is reported. A low-cost laser engraving machine equipped with a 450 nm high-power blue laser was used to remove the polyimide coating from the fused silica capillary by laser scanning the desired section. The entire process is automated and controlled in real time by software. This method can be easily adopted by many CE users for routine practice and is scalable for high-throughput production of detection windows across multiple capillaries.

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从毛细管电泳用熔融石英毛细管上去除聚酰亚胺涂层的简单方法。

本报告介绍了一种制作毛细管电泳（CE）检测窗的简单而经济的方法。使用配备 450 nm 高功率蓝色激光的低成本激光雕刻机，通过激光扫描所需的部分，去除熔融石英毛细管上的聚酰亚胺涂层。整个过程由软件自动实时控制。这种方法很容易被许多 CE 用户用于日常实践，并可扩展用于多个毛细管检测窗口的高通量生产。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Chromatography A 化学-分析化学

CiteScore

7.90

自引率

14.60%

发文量

742

审稿时长

45 days

期刊介绍： The Journal of Chromatography A provides a forum for the publication of original research and critical reviews on all aspects of fundamental and applied separation science. The scope of the journal includes chromatography and related techniques, electromigration techniques (e.g. electrophoresis, electrochromatography), hyphenated and other multi-dimensional techniques, sample preparation, and detection methods such as mass spectrometry. Contributions consist mainly of research papers dealing with the theory of separation methods, instrumental developments and analytical and preparative applications of general interest.