The spliceosome factor and RNA helicase Brr2a moonlights in miRNA production

IF 15.8 1区 生物学 Q1 PLANT SCIENCES
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引用次数: 0

Abstract

The secondary structure of pri-miRNAs determines the efficiency and accuracy of miRNA production. RNA helicase Brr2a, a key component of spliceosomes in Arabidopsis, can interact with the pri-miRNA processing machinery component HYL1 and fine-tune the structures of pri-miRNAs to enhance miRNA production, whether the pri-miRNAs contain introns or not.

Abstract Image

Abstract Image

剪接体因子和 RNA 螺旋酶 Brr2a 在 miRNA 生产中发挥着重要作用
pri-miRNA 的二级结构决定了 miRNA 生成的效率和准确性。RNA 螺旋酶 Brr2a 是拟南芥剪接体的一个关键组成部分,它能与 pri-miRNA 处理机制成分 HYL1 相互作用,微调 pri-miRNA 的结构,以提高 miRNA 的产生,无论 pri-miRNA 是否含有内含子。
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来源期刊
Nature Plants
Nature Plants PLANT SCIENCES-
CiteScore
25.30
自引率
2.20%
发文量
196
期刊介绍: Nature Plants is an online-only, monthly journal publishing the best research on plants — from their evolution, development, metabolism and environmental interactions to their societal significance.
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