Decision-making under uncertainty in healthy and cognitively impaired aging: A systematic review and meta-analysis

IF 3.5 3区医学 Q2 GERIATRICS & GERONTOLOGY

Archives of gerontology and geriatrics Pub Date : 2024-09-26 DOI:10.1016/j.archger.2024.105643

Ilaria Corbo, Francesca Favieri, Giuseppe Forte, Maria Casagrande

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引用次数: 0

Abstract

Decision-making (DM) is a complex cognitive behavior that involves gathering information and assessing options to identify choices under risky and uncertain conditions. Mild Cognitive Impairment (MCI) is a construct that includes a constellation of symptoms ranging from behavioral to cognitive impairments. This cluster of symptoms is frequently associated with poor decision-making. This study aimed to examine decision-making in pathological aging, specifically MCI. Therefore, we conducted a systematic review and meta-analysis to evaluate these relationships. According to the PRISMA 2020 Statement, nine studies were selected for the systematic review and eight for the meta-analysis. The results highlighted that MCI is associated with impaired decision-making in risky and ambiguous situations.

The systematic review reported that MCI was associated with impaired decision-making in ambiguous and in risky conditions. In contrast, the meta-analysis showed significant differences in overall decision-making and particularly in ambiguous conditions. This difficulty may be due to different impairments that affect MCI. The difficulty in advantageous decision-making could be due to different brain alterations in MCI, which could lead to problems in tasks requiring feedback-based responses.

These findings advance our understanding of decision-making in aging and suggest how decision-making alterations in MCI would affect the totality of executive functions and daily activities.

查看原文本刊更多论文

健康和认知功能受损的老年人在不确定情况下的决策：系统回顾和荟萃分析。

决策（DM）是一种复杂的认知行为，涉及收集信息和评估选项，以确定在风险和不确定条件下的选择。轻度认知障碍（MCI）是一种包括从行为到认知障碍等一系列症状的结构。这一系列症状往往与决策能力差有关。本研究旨在探讨病理衰老（尤其是 MCI）中的决策问题。因此，我们进行了系统回顾和荟萃分析来评估这些关系。根据 PRISMA 2020 声明，我们选择了 9 项研究进行系统回顾，8 项研究进行荟萃分析。结果表明，MCI 与风险和模糊情况下的决策能力受损有关。系统综述报告显示，MCI 与模糊和危险情况下的决策能力受损有关。与此相反，荟萃分析表明，在整体决策方面存在显著差异，尤其是在模棱两可的情况下。这种困难可能是由于影响 MCI 的不同损伤造成的。优势决策的困难可能是由于 MCI 患者的大脑发生了不同程度的改变，这可能会导致他们在完成需要基于反馈做出反应的任务时出现问题。这些研究结果加深了我们对衰老决策的理解，并表明MCI患者的决策改变将如何影响整个执行功能和日常活动。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archives of gerontology and geriatrics 医学-老年医学

CiteScore

7.30

自引率

5.00%

发文量

198

审稿时长

16 days

期刊介绍： Archives of Gerontology and Geriatrics provides a medium for the publication of papers from the fields of experimental gerontology and clinical and social geriatrics. The principal aim of the journal is to facilitate the exchange of information between specialists in these three fields of gerontological research. Experimental papers dealing with the basic mechanisms of aging at molecular, cellular, tissue or organ levels will be published. Clinical papers will be accepted if they provide sufficiently new information or are of fundamental importance for the knowledge of human aging. Purely descriptive clinical papers will be accepted only if the results permit further interpretation. Papers dealing with anti-aging pharmacological preparations in humans are welcome. Papers on the social aspects of geriatrics will be accepted if they are of general interest regarding the epidemiology of aging and the efficiency and working methods of the social organizations for the health care of the elderly.