{"title":"Colloidal droplet desiccation on a electrowetting-on-dielectric (EWOD) platform.","authors":"Udita Uday Ghosh, Trina Dhara, Janesh Bakshi, Kalpita Nath, Sunando DasGupta","doi":"10.1063/5.0209815","DOIUrl":null,"url":null,"abstract":"<p><p>The physics of the effects of electric field on the desiccation of colloidal droplets, comprising of dispersed negatively charged nanoparticles [2 <i>μ</i>l, 1(w/w. %)], are studied in a standard electrowetting-on-a-dielectric configuration. The extent of contact line pinning during evaporation is found to be a function of the magnitude of the applied voltage and quantified in terms of the dimensionless electrowetting number (<i>η</i>). The pinned contact line led to higher particle compaction as evidenced by the characterization of dried colloidal film thicknesses. Crack formation and their dynamics have been analyzed in detail to elicit the interplay of forces near the contact line region and on the compaction front. These aspects of crack formation are elucidated in the light of magnitude and polarity of the applied electric field. It is found to influence the crack front initiation velocity, the geometry, the number of cracks, and an attempt is made to explain the same via first principle-based approaches. Therefore, this study indicates the possibility of using electrowetting as a technique to fine-tune the crack formation behavior in thin colloidal films.</p>","PeriodicalId":8855,"journal":{"name":"Biomicrofluidics","volume":null,"pages":null},"PeriodicalIF":2.6000,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11449496/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomicrofluidics","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1063/5.0209815","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
Abstract
The physics of the effects of electric field on the desiccation of colloidal droplets, comprising of dispersed negatively charged nanoparticles [2 μl, 1(w/w. %)], are studied in a standard electrowetting-on-a-dielectric configuration. The extent of contact line pinning during evaporation is found to be a function of the magnitude of the applied voltage and quantified in terms of the dimensionless electrowetting number (η). The pinned contact line led to higher particle compaction as evidenced by the characterization of dried colloidal film thicknesses. Crack formation and their dynamics have been analyzed in detail to elicit the interplay of forces near the contact line region and on the compaction front. These aspects of crack formation are elucidated in the light of magnitude and polarity of the applied electric field. It is found to influence the crack front initiation velocity, the geometry, the number of cracks, and an attempt is made to explain the same via first principle-based approaches. Therefore, this study indicates the possibility of using electrowetting as a technique to fine-tune the crack formation behavior in thin colloidal films.
期刊介绍:
Biomicrofluidics (BMF) is an online-only journal published by AIP Publishing to rapidly disseminate research in fundamental physicochemical mechanisms associated with microfluidic and nanofluidic phenomena. BMF also publishes research in unique microfluidic and nanofluidic techniques for diagnostic, medical, biological, pharmaceutical, environmental, and chemical applications.
BMF offers quick publication, multimedia capability, and worldwide circulation among academic, national, and industrial laboratories. With a primary focus on high-quality original research articles, BMF also organizes special sections that help explain and define specific challenges unique to the interdisciplinary field of biomicrofluidics.
Microfluidic and nanofluidic actuation (electrokinetics, acoustofluidics, optofluidics, capillary)
Liquid Biopsy (microRNA profiling, circulating tumor cell isolation, exosome isolation, circulating tumor DNA quantification)
Cell sorting, manipulation, and transfection (di/electrophoresis, magnetic beads, optical traps, electroporation)
Molecular Separation and Concentration (isotachophoresis, concentration polarization, di/electrophoresis, magnetic beads, nanoparticles)
Cell culture and analysis(single cell assays, stimuli response, stem cell transfection)
Genomic and proteomic analysis (rapid gene sequencing, DNA/protein/carbohydrate arrays)
Biosensors (immuno-assay, nucleic acid fluorescent assay, colorimetric assay, enzyme amplification, plasmonic and Raman nano-reporter, molecular beacon, FRET, aptamer, nanopore, optical fibers)
Biophysical transport and characterization (DNA, single protein, ion channel and membrane dynamics, cell motility and communication mechanisms, electrophysiology, patch clamping). Etc...