{"title":"Laser-induced graphene/gold nanoparticle hybrid sensor for enhanced electrochemical detection of paracetamol.","authors":"Wenbang Yu, Xiaotian Xu, Tian Cao, Zihan Wei, Jing Tang, Min Zhang","doi":"10.1039/d4ay01627k","DOIUrl":null,"url":null,"abstract":"<p><p>This research presents a highly sensitive and selective electrochemical sensor for detecting paracetamol. The sensor is created using laser direct-writing on a flexible PI substrate to form LIG electrodes. Gold nanoparticles (AuNPs) are then synthesized on the working electrode through secondary laser reduction, resulting in an AuNPs/LIG composite. This combination enhances the sensor's electrochemical activity, electron transfer rate, and adsorption capacity. The sensor exhibits a linear response to paracetamol concentrations with a detection limit of 0.086 μM. Testing on Tylenol tablets and tap water showed good recovery rates. The sensor displays strong anti-interference, reproducibility, and stability, making it a promising tool for effective paracetamol monitoring in real-world situations.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":null,"pages":null},"PeriodicalIF":2.7000,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analytical Methods","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d4ay01627k","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
This research presents a highly sensitive and selective electrochemical sensor for detecting paracetamol. The sensor is created using laser direct-writing on a flexible PI substrate to form LIG electrodes. Gold nanoparticles (AuNPs) are then synthesized on the working electrode through secondary laser reduction, resulting in an AuNPs/LIG composite. This combination enhances the sensor's electrochemical activity, electron transfer rate, and adsorption capacity. The sensor exhibits a linear response to paracetamol concentrations with a detection limit of 0.086 μM. Testing on Tylenol tablets and tap water showed good recovery rates. The sensor displays strong anti-interference, reproducibility, and stability, making it a promising tool for effective paracetamol monitoring in real-world situations.
这项研究提出了一种用于检测扑热息痛的高灵敏度和高选择性电化学传感器。该传感器采用激光直写技术在柔性 PI 基底上形成 LIG 电极。然后通过二次激光还原在工作电极上合成金纳米粒子(AuNPs),形成 AuNPs/LIG 复合材料。这种组合增强了传感器的电化学活性、电子转移率和吸附能力。该传感器对扑热息痛浓度呈线性响应,检测限为 0.086 μM。在泰诺片和自来水上进行的测试表明回收率良好。该传感器具有很强的抗干扰性、再现性和稳定性,是在实际环境中有效监测扑热息痛的理想工具。