Prophylactic dextrose gel use in newborns at risk for hypoglycemia

IF 2.4 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Journal of Perinatology Pub Date : 2024-10-03 DOI:10.1038/s41372-024-02133-9

Venkatasai Devarapalli, Makenzie Niven, Jared Canonigo, Beverly Spray, Indirapriya Avulakunta, Jared Beavers, Jennifer Andrews, Vikramaditya Dumpa

引用次数: 0

Abstract

To assess the impact of prophylactic dextrose gel on short-term outcomes in infants at risk for hypoglycemia. Retrospective, single-center, observational study of neonates at risk for hypoglycemia -infants of diabetic mothers, large and small for gestational age infants, born between January 2015 and May 2023. Infants were categorized into two groups for analysis. 1. Pre- dextrose gel (01/2015 to 04/2018, n = 788) and 2. Dextrose gel (01/2019 to 05/2023, n = 1495). Infant demographic data and outcome variables were compared between the two groups. 2283 infants were eligible. Prophylactic dextrose gel use was associated with decreased admission rates to NICU secondary to hypoglycemia (2.7% vs. 6.5%), reduced incidence of hypoglycemia (32% vs. 43.3%), and higher exclusive breastmilk use at discharge (47% vs. 37.3%). The use of prophylactic dextrose gel in certain high-risk newborns was associated with improved patient outcomes.

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在有低血糖风险的新生儿中预防性使用葡萄糖凝胶。

目的：评估预防性葡萄糖凝胶对低血糖风险婴儿短期疗效的影响：评估预防性葡萄糖凝胶对低血糖风险婴儿短期预后的影响：回顾性、单中心、观察性研究，对象为 2015 年 1 月至 2023 年 5 月间出生的有低血糖风险的新生儿--母亲为糖尿病患者的婴儿、胎龄大的婴儿和胎龄小的婴儿。婴儿分为两组进行分析。1.葡萄糖凝胶前（01/2015 至 04/2018，n = 788）和 2.葡萄糖凝胶（01/2019 至 05/2023，n = 1495）。对两组婴儿的人口统计学数据和结果变量进行了比较。使用预防性葡萄糖凝胶可降低因低血糖而入住新生儿重症监护室的比例（2.7% vs. 6.5%），降低低血糖发生率（32% vs. 43.3%），提高出院时纯母乳使用率（47% vs. 37.3%）：结论：对某些高风险新生儿使用预防性葡萄糖凝胶可改善患者的预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Perinatology 医学-妇产科学

CiteScore

5.40

自引率

6.90%

发文量

284

审稿时长

3-8 weeks

期刊介绍： The Journal of Perinatology provides members of the perinatal/neonatal healthcare team with original information pertinent to improving maternal/fetal and neonatal care. We publish peer-reviewed clinical research articles, state-of-the art reviews, comments, quality improvement reports, and letters to the editor. Articles published in the Journal of Perinatology embrace the full scope of the specialty, including clinical, professional, political, administrative and educational aspects. The Journal also explores legal and ethical issues, neonatal technology and product development. The Journal’s audience includes all those that participate in perinatal/neonatal care, including, but not limited to neonatologists, perinatologists, perinatal epidemiologists, pediatricians and pediatric subspecialists, surgeons, neonatal and perinatal nurses, respiratory therapists, pharmacists, social workers, dieticians, speech and hearing experts, other allied health professionals, as well as subspecialists who participate in patient care including radiologists, laboratory medicine and pathologists.