Effectiveness of influenza vaccines in children aged 6 to 59 months: a test-negative case-control study at primary care and hospital level, Spain 2023/24.

IF 9.9 2区医学 Q1 INFECTIOUS DISEASES

Eurosurveillance Pub Date : 2024-10-01 DOI:10.2807/1560-7917.ES.2024.29.40.2400618

Gloria Pérez-Gimeno, Clara Mazagatos, Nicola Lorusso, Luca Basile, Isabel Martínez-Pino, Francisca Corpas Burgos, Noa Batalla Rebolla, Mercedes B Rumayor Zarzuelo, Blanca Andreu Ivorra, Jaume Giménez Duran, Daniel Castrillejo, Inés Guiu Cañete, Marta Huerta Huerta, Marta García Becerril, Violeta Ramos Marín, Inmaculada Casas, Francisco Pozo, Susana Monge

引用次数: 0

Abstract

During 2023/24, all children aged 6 to 59 months were targeted for seasonal influenza vaccination in Spain nationally. Using a test-negative case-control design with sentinel surveillance data, we estimated adjusted influenza vaccine effectiveness (IVE) against any influenza type to be 70% (95% confidence interval (CI): 51 to 81%) for primary care patients with acute respiratory illness (ARI) and 77% (95% CI: 21 to 93%) for hospitalised patients with severe ARI. In primary care, where most subtyped viruses (61%; 145/237) were A(H1N1), adjusted IVE was 77% (95% CI: 56 to 88%) against A(H1N1)pdm09.

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6 至 59 个月儿童接种流感疫苗的效果：西班牙 2023/24 年初级保健和医院水平的测试阴性病例对照研究。

2023/24 年期间，西班牙全国所有 6 至 59 个月大的儿童都将接种季节性流感疫苗。通过使用哨点监测数据进行阴性病例对照设计，我们估计调整后的流感疫苗对任何流感类型的有效率（IVE）为：初级医疗机构的急性呼吸道疾病（ARI）患者为 70%（95% 置信区间：51% 至 81%），住院的严重急性呼吸道疾病患者为 77%（95% 置信区间：21% 至 93%）。在基层医疗机构，大多数亚型病毒（61%；145/237）都是 A(H1N1)，针对 A(H1N1)pdm09 的调整 IVE 为 77%（95% CI：56% 至 88%）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Eurosurveillance INFECTIOUS DISEASES-

CiteScore

32.70

自引率

2.10%

发文量

430

审稿时长

3-8 weeks

期刊介绍： Eurosurveillance is a European peer-reviewed journal focusing on the epidemiology, surveillance, prevention, and control of communicable diseases relevant to Europe.It is a weekly online journal, with 50 issues per year published on Thursdays. The journal includes short rapid communications, in-depth research articles, surveillance reports, reviews, and perspective papers. It excels in timely publication of authoritative papers on ongoing outbreaks or other public health events. Under special circumstances when current events need to be urgently communicated to readers for rapid public health action, e-alerts can be released outside of the regular publishing schedule. Additionally, topical compilations and special issues may be provided in PDF format.