Fatality from COVID-19 does not affect palliative care duration among patients with advanced cancer: a retrospective cohort study.

Abstract

Background: Jomar et al. demonstrated that death due to COVID-19 did not affect the time under exclusive palliative care among patients with advanced cancer, even during the first year of the pandemic caused by a hitherto little-known disease.

Background: ◼ Fatality due to COVID-19 does not alter the time under oncological palliative care.

Background: ◼ The retrospective design of this pioneering study allows causal inference.

Background: ◼ Access to oncological palliative care frequently approaches terminality of life.

Objective: This study aimed at investigating the extent to which COVID-19-induced fatalities affect the duration of palliative care among patients with advanced cancer.

Methods: A retrospective cohort study was conducted at the Palliative Care Unit of the Brazilian Instituto Nacional de Câncer in Rio de Janeiro, Brazil, on 1,104 advanced cancer patients who died under exclusive palliative care between March 11, 2020, and March 31, 2021. Wilcoxon rank-sum (Mann-Whitney U) and log-rank tests were performed to examine statistical differences between the medians of time, and the Kaplan-Meier estimator was used to graphically illustrate survival over time under exclusive palliative care contingent upon the underlying causes of death of the two experimental groups (cancer versus COVID-19).

Results: A total of 133 (12.05%) patients succumbed to COVID-19. In both groups, the median time under exclusive palliative care was less than one month. The exclusive palliative care survival curves did not exhibit any statistically significant difference between the groups.

Conclusion: Death due to COVID-19 did not modify the duration of exclusive palliative care among patients with advanced cancer.