Phenolic compounds from the aerial parts of Rhodiola rosea in Japan, and their antioxidant activity and chemical adaptation to alpine environment.

IF 1.9 3区化学 Q3 CHEMISTRY, APPLIED

Natural Product Research Pub Date : 2024-10-03 DOI:10.1080/14786419.2024.2408662

Tsukasa Iwashina, Takahisa Nakane, Yuko Ishikawa-Takano, Hari Prasad Devkota

引用次数: 0

Abstract

Twelve flavonoids (1-12) including a new flavonol glycoside, hibiscetin 3-O-glucopyranoside-8-O-glucuronopyranoside, ten known galloylglucoses (13-22) and three known phenolic acids (23-25) were isolated from the aerial parts of Rhodiola rosea growing in Japan. Their chemical structures were elucidated by UV-vis spectra, LC-MS, HR-MS, acid hydrolysis, NMR, and/or HPLC, and TLC comparisons with authentic samples. Antioxidant activity of major 14 compounds was measured by H-ORAC method, and two flavonols, herbacetin 3-O-glucoside-8-O-glucuronide, and gossypetin 3-O-glucuronide-8-O-glucoside, showed the strongest activity. Moreover, chemical adaptation to severe alpine environment of R. rosea was discussed.

查看原文本刊更多论文

日本红景天气生部分的酚类化合物及其抗氧化活性和对高寒环境的化学适应性。

从生长在日本的红景天的气生部分分离出了 12 种黄酮类化合物（1-12），包括一种新的黄酮醇苷--木槿素 3-O-吡喃葡萄糖苷-8-O-吡喃葡萄糖苷、10 种已知的五倍子葡萄糖（13-22）和 3 种已知的酚酸（23-25）。通过紫外-可见光谱、LC-MS、HR-MS、酸水解、核磁共振和/或 HPLC 以及 TLC 与真实样品的比较，阐明了它们的化学结构。采用 H-ORAC 法测定了主要 14 种化合物的抗氧化活性，其中两种黄酮醇类化合物--香草素 3-O-葡萄糖苷-8-O-葡萄糖醛酸苷和格桑花素 3-O-葡萄糖苷-8-O-葡萄糖醛酸苷的活性最强。此外，还讨论了蔷薇属植物对严酷高寒环境的化学适应性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Natural Product Research 化学-医药化学

CiteScore

5.10

自引率

9.10%

发文量

605

审稿时长

2.1 months

期刊介绍： The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.