Clozapine monitoring requirements: is it time for an update?

IF 8.7 1区医学 Q1 PSYCHIATRY

British Journal of Psychiatry Pub Date : 2024-10-03 DOI:10.1192/bjp.2024.150

Emilio Fernandez-Egea, Robert A McCutcheon

引用次数: 0

Abstract

Oloyede and colleagues advocate for updating haematological monitoring requirements for clozapine, arguing that current protocols overestimate the risk of clozapine-induced agranulocytosis. Their research suggests that stringent monitoring may unnecessarily limit access to clozapine, a crucial treatment for resistant schizophrenia. The editorial supports calls for international consensus to carefully weigh the pros and cons of relaxing monitoring guidelines while ensuring comprehensive care for patients.

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氯氮平监测要求：是时候更新了吗？

Oloyede 及其同事主张更新氯氮平的血液监测要求，认为目前的方案高估了氯氮平诱发粒细胞减少症的风险。他们的研究表明，严格的监测可能会不必要地限制氯氮平的使用，而氯氮平是治疗耐药性精神分裂症的重要药物。这篇社论支持国际共识的呼吁，即在确保为患者提供全面治疗的同时，仔细权衡放宽监测指南的利弊。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

British Journal of Psychiatry 医学-精神病学

CiteScore

13.70

自引率

1.90%

发文量

184

审稿时长

4-8 weeks

期刊介绍： The British Journal of Psychiatry (BJPsych) is a renowned international journal that undergoes rigorous peer review. It covers various branches of psychiatry, with a specific focus on the clinical aspects of each topic. Published monthly by the Royal College of Psychiatrists, this journal is dedicated to enhancing the prevention, investigation, diagnosis, treatment, and care of mental illness worldwide. It also strives to promote global mental health. In addition to featuring authoritative original research articles from across the globe, the journal includes editorials, review articles, commentaries on contentious issues, a comprehensive book review section, and a dynamic correspondence column. BJPsych is an essential source of information for psychiatrists, clinical psychologists, and other professionals interested in mental health.