The association between thyroid disease and hearing loss: a meta-analysis.

IF 1.2 4区医学 Q3 OTORHINOLARYNGOLOGY

Acta Oto-Laryngologica Pub Date : 2024-09-01 Epub Date: 2024-10-02 DOI:10.1080/00016489.2024.2404614

Li Gu, Wei Guo, Xinli Wang, Chuan Yue

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引用次数: 0

Abstract

Background: It has been shown that there is a link between thyroid-related diseases and hearing loss.

Objectives: The purpose of this study is to investigate the relationship between thyroid-related diseases and hearing loss by conducting a meta-analysis.

Material and methods: A thorough search was carried out in the following electronic databases: PubMed, Cochrane Library, Embase, Web of Science, Google Scholar, Semantic Scholar, and ResearchRabbit. The chi-square test and the I² index examined the research's heterogeneity. A funnel plot and the Eger test were used to examine publication-biased effects.

Results: A total of 48,507 individuals (6482 hypothyroid patients, 4162 hearing loss patients, and 37863 controls) were included in this meta-analysis of 18 research. Individuals with hypothyroidism had a 1.69-fold increased risk of hearing loss compared to those without the condition (OR: 1.69; 95% CI: 1.11-2.57, p < 0.001). among hypothyroidism, the prevalence of hearing loss was 24% (EC: 0.24; 95% CI: 0.11-0.39, p = 0.00), while among hearing-impaired individuals, the prevalence of hypothyroidism was 7% (EC: 0.21; 95% CI: 0.07-0.40).

Conclusion: This study demonstrated how thyroid dysfunction can raise the chance of hearing loss. To completely comprehend the underlying mechanisms and create efficient treatments for this illness, more study is required.

查看原文本刊更多论文

甲状腺疾病与听力损失之间的关系：一项荟萃分析。

背景：甲状腺相关疾病与听力损失之间存在联系：甲状腺相关疾病与听力损失之间存在联系：本研究的目的是通过荟萃分析研究甲状腺相关疾病与听力损失之间的关系：在以下电子数据库中进行了全面搜索：PubMed、Cochrane Library、Embase、Web of Science、Google Scholar、Semantic Scholar 和 ResearchRabbit。卡方检验和 I2 指数检验了研究的异质性。漏斗图和艾格检验用于检验发表偏倚效应：共有 48507 人（6482 名甲减患者、4162 名听力损失患者和 37863 名对照组）被纳入了这项对 18 项研究进行的荟萃分析。与无甲状腺功能减退症的患者相比，甲状腺功能减退症患者听力损失的风险增加了1.69倍（OR：1.69；95% CI：1.11-2.57，P = 0.00），而在听力受损患者中，甲状腺功能减退症的患病率为7%（EC：0.21；95% CI：0.07-0.40）：这项研究表明，甲状腺功能障碍会增加听力损失的几率。结论：本研究证明了甲状腺功能障碍会增加听力损失的几率，要想完全理解其潜在机制并创造出有效的治疗方法，还需要进行更多的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Oto-Laryngologica 医学-耳鼻喉科学

CiteScore

2.50

自引率

0.00%

发文量

审稿时长

3-6 weeks

期刊介绍： Acta Oto-Laryngologica is a truly international journal for translational otolaryngology and head- and neck surgery. The journal presents cutting-edge papers on clinical practice, clinical research and basic sciences. Acta also bridges the gap between clinical and basic research.