Evaluation of Frontal QRS-T Angle in Children With ADHD and Healthy Controls.

IF 2.7 3区医学 Q2 PSYCHIATRY

Journal of Attention Disorders Pub Date : 2024-10-02 DOI:10.1177/10870547241288353

Fethiye Kılıçaslan, Aybike Tan, Zulkif Tanriverdi

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引用次数: 0

Abstract

Introduction: Conflicting findings exist regarding the link between attention deficit hyperactivity disorder (ADHD) and cardiovascular diseases. This study aimed to evaluate the frontal QRS-T (fQRS-T) angle and its correlation with symptom severity in children diagnosed with ADHD.

Methods: The study population consisted of 172 patients diagnosed with ADHD (120 drug naive and 52 drug positive) and 82 healthy controls. ADHD symptoms were assessed using the Atilla Turgay DSM-IV-Based Screening and Assessment Scale for Disruptive Conduct Disorders (T-DSM-IV-Scale). The fQRS-T angle and corrected QT (QTc) interval were obtained from the automated reports of 12-lead electrocardiography device for each patient.

Results: QTc interval and fQRS-T angle were significantly different among the groups. Post hoc analyses showed that QTc interval and fQRS-T angle of ADHD drug naive and ADHD drug positive patients were significantly higher than the healthy control groups. However, there was no significant difference between drug naive and drug positive patients regarding QTc interval and fQRS-T angle. Both QTc interval and fQRS-T angle showed positive correlations with the severity of ADHD symptoms (r = 0.263, p = .001 and r = 0.175, p = .023 respectively).

Conclusion: We found that fQRS-T angle was significantly wider in children with ADHD. Therefore, we suggest that fQRS-T angle may help in cardiovascular risk assessment in children with ADHD.

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评估多动症儿童和健康对照组的额叶 QRS-T 角。

导言：关于注意力缺陷多动障碍（ADHD）与心血管疾病之间的联系，存在着相互矛盾的研究结果。本研究旨在评估被诊断为ADHD的儿童额叶QRS-T（fQRS-T）角及其与症状严重程度的相关性：研究对象包括172名确诊为多动症的患者（120名药物未检测出阳性，52名药物检测出阳性）和82名健康对照者。ADHD症状使用基于阿蒂拉-图尔盖DSM-IV的破坏性行为障碍筛查和评估量表（T-DSM-IV量表）进行评估。每位患者的 fQRS-T 角和校正 QT（QTc）间期均来自 12 导联心电图仪的自动报告：结果：各组间的 QTc 间期和 fQRS-T 角有显著差异。事后分析表明，ADHD药物天真患者和ADHD药物阳性患者的QTc间期和fQRS-T角明显高于健康对照组。然而，在QTc间期和fQRS-T角方面，药物幼稚组和药物阳性组之间没有明显差异。QTc间期和fQRS-T角与ADHD症状的严重程度呈正相关（分别为r = 0.263，p = .001和r = 0.175，p = .023）：结论：我们发现，多动症儿童的 fQRS-T 角明显增宽。结论：我们发现，ADHD 儿童的 fQRS-T 角明显更宽，因此，我们认为 fQRS-T 角可能有助于评估 ADHD 儿童的心血管风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Attention Disorders PSYCHIATRY-

CiteScore

7.60

自引率

6.70%

发文量

审稿时长

6-12 weeks

期刊介绍： Journal of Attention Disorders (JAD) focuses on basic and applied science concerning attention and related functions in children, adolescents, and adults. JAD publishes articles on diagnosis, comorbidity, neuropsychological functioning, psychopharmacology, and psychosocial issues. The journal also addresses practice, policy, and theory, as well as review articles, commentaries, in-depth analyses, empirical research articles, and case presentations or program evaluations.