Psychiatric disorders from EEG signals through deep learning models

Abstract

Psychiatric disorders present diagnostic challenges due to individuals concealing their genuine emotions, and traditional methods relying on neurophysiological signals have limitations. Our study proposes an improved EEG-based diagnostic model employing Deep Learning (DL) techniques to address this. By experimenting with DL models on EEG data, we aimed to enhance psychiatric disorder diagnosis, offering promising implications for medical advancements. We utilized a dataset of 945 individuals, including 850 patients and 95 healthy subjects, focusing on six main and nine specific disorders. Quantitative EEG data were analyzed during resting states, featuring power spectral density (PSD) and functional connectivity (FC) across various frequency bands. Employing artificial neural networks (ANN), K nearest neighbors (KNN), Long short-term memory (LSTM), bidirectional Long short-term memory (Bi LSTM), and a hybrid CNN-LSTM model, we performed binary classification. Remarkably, all proposed models outperformed previous approaches, with the ANN achieving 96.83 % accuracy for obsessive-compulsive disorder using entire band features. CNN-LSTM attained the same accuracy for adjustment disorder, while KNN and LSTM achieved 98.94 % accuracy for acute stress disorder using specific feature sets. Notably, KNN and Bi-LSTM models reached 97.88 % accuracy for predicting obsessive-compulsive disorder. These findings underscore the potential of EEG as a cost-effective and accessible diagnostic tool for psychiatric disorders, complementing traditional methods like MRI. Our study's advanced DL models show promise in enhancing psychiatric disorder detection and monitoring, with significant implications for clinical application, inspiring hope for improved patient care and outcomes. The potential of EEG as a diagnostic tool for psychiatric disorders is substantial, as it can lead to improved patient care and outcomes in the field of psychiatry.